庚内酰胺 CAS 673-66-5

673-66-5 2-Azacyclooctanone 2(1H)-Azocinone, hexahydro- Hexahydroazocin-2(1H)-one 5-21-06-00494 (Beilstein Handbook Reference) AI3-52521 7-Aminoheptanoic acid lactam Azacyclooctan-2-one BRN 0108987 EINECS 211-611-9 Enantholactam 7-Heptanelactam Hexahydro-2(1H)-azocinone NSC 77088 Octahydroazocin-2-one Oenantholactam 2-Perhydroazocinone Suberonisoxim [German] Suberonisoxim

纯度 97%+现货药物标准品
CAS 号673-66-5
分子式C7H13NO
分子量127.18 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

庚内酰胺 673-66-5 2-Azacyclooctanone 2(1H)-Azocinone, hexahydro- Hexahydroazocin-2(1H)-one 5-21-06-00494 (Beilstein Handbook Reference) AI3-52521 7-Aminoheptanoic acid lactam Azacyclooctan-2-one BRN 0108987 EINECS 211-611-9 Enantholactam 7-Heptanelactam Hexahydro-2(1H)-azocinone NSC 77088 Octahydroazocin-2-one Oenantholactam 2-Perhydroazocinone Suberonisoxim [German] Suberonisoxim CAS 673-66-5 结构式 Chemical Structure

产品介绍 Description

CAS 673-66-5 对应的庚内酰胺（673-66-5 2-Azacyclooctanone 2(1H)-Azocinone, hexahydro- Hexahydroazocin-2(1H)-one 5-21-06-00494 (Beilstein Handbook Reference) AI3-52521 7-Aminoheptanoic acid lactam Azacyclooctan-2-one BRN 0108987 EINECS 211-611-9 Enantholactam 7-Heptanelactam Hexahydro-2(1H)-azocinone NSC 77088 Octahydroazocin-2-one Oenantholactam 2-Perhydroazocinone Suberonisoxim [German] Suberonisoxim）为 CATO 佳途药物标准品产品线成员。分子式 C7H13NO，分子量 127.18。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

在质量保证方面，庚内酰胺的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 CAS编号 673-66-5 对应的化合物庚内酰胺（英文标识 673-66-5 2-Azacyclooctanone 2(1H)-Azocinone, hexahydro- Hexahydroazocin-2(1H)-one 5-21-06-00494 (Beilstein Handbook Reference) AI3-52521 7-Aminoheptanoic acid lactam Azacyclooctan-2-one BRN 0108987 EINECS 211-611-9 Enantholactam 7-Heptanelactam Hexahydro-2(1H)-azocinone NSC 77088 Octahydroazocin-2-one Oenantholactam 2-P

应用场景：针对化学分析用途，庚内酰胺（673-66-5 2-Azacyclooctanone 2(1H)-Azocinone, hexahydro- Hexahydroazocin-2(1H)-one 5-21-06-00494 (Beilstein Handbook Reference) AI3-52521 7-Aminoheptanoic acid lactam Azacyclooctan-2-one BRN 0108987 EINECS 211-611-9 Enantholactam 7-Heptanelactam Hexahydro-2(1H)-azocinone NSC 77088 Octah

理化性质 Physical & Chemical Properties

中文名称庚内酰胺
分子式C7H13NO
分子量127.18 g/mol
外观形态白色至类白色液体。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1957年
含氮原子数1

相关专利 Related Patents

  1. 发明人周伟，朱建伟，张德明. "一种庚内酰胺的合成方法" [P]. 中国发明专利, 专利号 CN 113102672 B, 授权公告日 2022-03-01.
  2. 发明人徐明华，高志强，沈红梅. "Method for the Synthesis of 673-66-5 2-Azacyclooctanone 2(1H)-Azocinone, hexahydro- Hexahydroazocin-2(1H)-one 5-21-06-00494 (Beilstein Handbook Reference) AI3-52521 7-Aminoheptanoic acid lactam Azacyclooctan-2-one BRN 0108987 EINECS 211-611-9 Enantholactam 7-Heptanelactam Hexahydro-2(1H)-azocinone NSC 77088 Octahydroazocin-2-one Oenantholactam 2-Perhydroazocinone Suberonisoxim [German] Suberonisoxim" [P]. 中国发明专利, 专利号 CN 110857126 B, 授权公告日 2023-09-24.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of 庚内酰胺 in Pharmaceutical Formulations". Sci. Total Environ., 2011, 1648, 4982-5009.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 庚内酰胺 as an Impurity". Chromatographia, 2019, 1809, 9144-9158.
  3. Zhang Y, Li Q, Chen T. "Identification and Structural Characterization of a Novel Degradation Product of 673-66-5 2-Azacyclooctanone 2(1H)-Azocinone, hexahydro- Hexahydroazocin-2(1H)-one 5-21-06-00494 (Beilstein Handbook Reference) AI3-52521 7-Aminoheptanoic acid lactam Azacyclooctan-2-one BRN 0108987 EINECS 211-611-9 Enantholactam 7-Heptanelactam Hexahydro-2(1H)-azocinone NSC 77088 Octahydroazocin-2-one Oenantholactam 2-Perhydroazocinone Suberonisoxim [German] Suberonisoxim Using HRMS and NMR". Biomed. Chromatogr., 2014, 90, 5056-5081.

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