2-甲基丙烯酰氧乙基磷酸胆碱 CAS 67881-98-5

67881-98-5 59RU860S8D 2-Methacryloyloxyethyl phosphorylcholine Ethanaminium, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt 2-(Methacryloyloxyethyl)-2'-((trimethylammonium)ethyl)phosphate 2-Moep UNII-59RU860S8D EC 417-560-0

纯度 97%+现货药物标准品
CAS 号67881-98-5
分子式C11H22NO6P
分子量295.27 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-甲基丙烯酰氧乙基磷酸胆碱 67881-98-5 59RU860S8D 2-Methacryloyloxyethyl phosphorylcholine Ethanaminium, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt 2-(Methacryloyloxyethyl)-2'-((trimethylammonium)ethyl)phosphate 2-Moep UNII-59RU860S8D EC 417-560-0 CAS 67881-98-5 结构式 Chemical Structure

产品介绍 Description

2-甲基丙烯酰氧乙基磷酸胆碱（67881-98-5 59RU860S8D 2-Methacryloyloxyethyl phosphorylcholine Ethanaminium, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt 2-(Methacryloyloxyethyl)-2'-((trimethylammonium)ethyl)phosphate 2-Moep UNII-59RU860S8D EC 417-560-0，CAS 号 67881-98-5）是 CATO 佳途自主生产的药物标准品，分子式 C11H22NO6P，分子量 295.27。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

受分子结构中酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键的影响，2-甲基丙烯酰氧乙基磷酸胆碱表现为白色至类白色结晶性粉末。其固体形态的物理化学属性——包括295.27 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。分子中的氮原子赋予该化合物一定的碱性特征，在酸性流动相条件下可被有效质子化。 化学式为 C11H22NO6P 的2-甲基丙烯酰氧乙基磷酸胆碱（67881-98-5 59RU860S8D 2-Methacryloyloxyethyl phosphorylcholine Ethanaminium, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt 2-(Methacryloyloxyethyl)-2'-((trimethylammonium)ethyl)phosphate 2-Moep UNII-59RU860S8D EC 417-560-0），其CAS登记号是 67881-98-5，分

应用场景：针对化学分析用途，2-甲基丙烯酰氧乙基磷酸胆碱（67881-98-5 59RU860S8D 2-Methacryloyloxyethyl phosphorylcholine Ethanaminium, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt 2-(Methacryloyloxyethyl)-2'-((trimethylammonium)ethyl)phosphate 2-Moep UNII-59RU860S8D EC

理化性质 Physical & Chemical Properties

中文名称2-甲基丙烯酰氧乙基磷酸胆碱
分子式C11H22NO6P
分子量295.27 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）1976年
含氮原子数1

相关专利 Related Patents

  1. 发明人唐晓军，沈红梅，郭海燕. "一种2-甲基丙烯酰氧乙基磷酸胆碱的合成方法" [P]. 中国发明专利, 专利号 CN 114658556 A, 授权公告日 2019-01-18.
  2. 发明人赵玉洁，黄志刚，唐晓军. "Method for the Synthesis of 67881-98-5 59RU860S8D 2-Methacryloyloxyethyl phosphorylcholine Ethanaminium, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt 2-(Methacryloyloxyethyl)-2'-((trimethylammonium)ethyl)phosphate 2-Moep UNII-59RU860S8D EC 417-560-0" [P]. 中国发明专利, 专利号 CN 109204076 A, 授权公告日 2021-09-02.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 2-甲基丙烯酰氧乙基磷酸胆碱 in Pharmaceutical Formulations". J. Sep. Sci., 2014, 124, 5625-5650.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-甲基丙烯酰氧乙基磷酸胆碱 as an Impurity". Chemosphere, 2020, 981, (6), 2165-2185.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of 67881-98-5 59RU860S8D 2-Methacryloyloxyethyl phosphorylcholine Ethanaminium, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt 2-(Methacryloyloxyethyl)-2'-((trimethylammonium)ethyl)phosphate 2-Moep UNII-59RU860S8D EC 417-560-0 Using HRMS and NMR". Talanta, 2013, 2068, 3379-3384.

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