聚(二甲基硅氧烷)，氯封端 CAS 67923-13-1

67923-13-1 Siloxanes and Silicones, di-Me, chlorine-terminated alpha,omega-Dichloropolydimethyl siloxane Dichloropoly(dimethylsiloxane) Polydimethylsiloxane, chloro end-blocked Poly(oxy(dimethylsilylene)), alpha-chlorodimethylsilyl-omega-chloro- alpha,omega-Dichloropolydimethylsiloxane

纯度 97%+现货药物标准品
CAS 号67923-13-1
分子式C2H7ClOSi C2H6OSi
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

聚(二甲基硅氧烷)，氯封端 67923-13-1 Siloxanes and Silicones, di-Me, chlorine-terminated alpha,omega-Dichloropolydimethyl siloxane Dichloropoly(dimethylsiloxane) Polydimethylsiloxane, chloro end-blocked Poly(oxy(dimethylsilylene)), alpha-chlorodimethylsilyl-omega-chloro- alpha,omega-Dichloropolydimethylsiloxane CAS 67923-13-1 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的聚(二甲基硅氧烷)，氯封端（67923-13-1 Siloxanes and Silicones, di-Me, chlorine-terminated alpha,omega-Dichloropolydimethyl siloxane Dichloropoly(dimethylsiloxane) Polydimethylsiloxane, chloro end-blocked Poly(oxy(dimethylsilylene)), alpha-chlorodimethylsilyl-omega-chloro- alpha,omega-Dichloropolydimethylsiloxane）为药物标准品，CAS 登记号 67923-13-1，分子式 C2H7ClOSi C2H6OSi。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括聚(二甲基硅氧烷)，氯封端在内的目标物的控制。 化学式为 C2H7ClOSi C2H6OSi 的聚(二甲基硅氧烷)，氯封端（67923-13-1 Siloxanes and Silicones, di-Me, chlorine-terminated alpha,omega-Dichloropolydimethyl siloxane Dichloropoly(dimethylsiloxane) Polydimethylsiloxane, chloro end-blocked Poly(oxy(dimethylsilylene)), alpha-chlorodimethylsilyl-omega-chloro- alpha,omega-Dichloropolydimethylsiloxane），其CAS登记号是 67923-13-1，分子量为 184.77 g/mol。 受分子结构中羧酸类，含羟基，含醚键，含氯取代的影响，聚(二甲基硅氧烷)，氯封端表现为白色至类白色结晶性粉末。（具有轻微卤代物特征气味）。其固体形态的物理化学属

应用场景：聚(二甲基硅氧烷)，氯封端（67923-13-1 Siloxanes and Silicones, di-Me, chlorine-terminated alpha,omega-Dichloropolydimethyl siloxane Dichloropoly(dimethylsiloxane) Polydimethylsiloxane, chloro end-blocked Poly(oxy(dimethylsilylene)), alpha-chlorodimethylsilyl-omega-chloro- alpha,omega-Dichloropolydimethylsiloxane

理化性质 Physical & Chemical Properties

中文名称聚(二甲基硅氧烷)，氯封端
分子式C2H7ClOSi C2H6OSi
分子量184.77 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-2.0
CAS登记年份（估）1976年
卤素含量Cl取代

相关专利 Related Patents

  1. 发明人杨光，郭海燕，罗永刚. "一种聚(二甲基硅氧烷)，氯封端的合成方法" [P]. 中国发明专利, 专利号 CN 110793608 A, 授权公告日 2017-12-02.
  2. 发明人林芳，孙丽萍，徐明华. "Method for the Synthesis of 67923-13-1 Siloxanes and Silicones, di-Me, chlorine-terminated alpha,omega-Dichloropolydimethyl siloxane Dichloropoly(dimethylsiloxane) Polydimethylsiloxane, chloro end-blocked Poly(oxy(dimethylsilylene)), alpha-chlorodimethylsilyl-omega-chloro- alpha,omega-Dichloropolydimethylsiloxane" [P]. 中国发明专利, 专利号 CN 114043777 A, 授权公告日 2025-02-10.
  3. Thompson G K, Williams B T, Schröder R. "A Process for Preparing High-Purity 67923-13-1 Siloxanes and Silicones, di-Me, chlorine-terminated alpha,omega-Dichloropolydimethyl siloxane Dichloropoly(dimethylsiloxane) Polydimethylsiloxane, chloro end-blocked Poly(oxy(dimethylsilylene)), alpha-chlorodimethylsilyl-omega-chloro- alpha,omega-Dichloropolydimethylsiloxane" [P]. US Patent, US 10221979 B2, 2015-01-26.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 聚(二甲基硅氧烷)，氯封端 in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2015, 691, 4325-4333.
  2. Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of 聚(二甲基硅氧烷)，氯封端 as an Impurity". Anal. Chem., 2018, 1659, 8443-8459.
  3. Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 67923-13-1 Siloxanes and Silicones, di-Me, chlorine-terminated alpha,omega-Dichloropolydimethyl siloxane Dichloropoly(dimethylsiloxane) Polydimethylsiloxane, chloro end-blocked Poly(oxy(dimethylsilylene)), alpha-chlorodimethylsilyl-omega-chloro- alpha,omega-Dichloropolydimethylsiloxane Using HRMS and NMR". J. Chromatogr. A, 2019, 334, 8374-8385.

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