甲基甲硫基吡嗪 CAS 67952-65-2

67952-65-2 Methyl(methylthio)pyrazine Pyrazine, methyl(methylthio)- EINECS 267-918-3 FEMA No. 3208 2-Methyl-3(or 5 or 6)-(methylthio)pyrazine (Methylthio)(methyl)pyrazine (Methylthio)methylpyrazine (mixture of isomers) 3(or 5 or 6)-(Methylthio)-2-methylpyrazine

纯度 97%+现货药物标准品
CAS 号67952-65-2
分子式2*C6H14N2S
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

甲基甲硫基吡嗪 67952-65-2 Methyl(methylthio)pyrazine Pyrazine, methyl(methylthio)- EINECS 267-918-3 FEMA No. 3208 2-Methyl-3(or 5 or 6)-(methylthio)pyrazine (Methylthio)(methyl)pyrazine (Methylthio)methylpyrazine (mixture of isomers) 3(or 5 or 6)-(Methylthio)-2-methylpyrazine CAS 67952-65-2 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品甲基甲硫基吡嗪（67952-65-2 Methyl(methylthio)pyrazine Pyrazine, methyl(methylthio)- EINECS 267-918-3 FEMA No. 3208 2-Methyl-3(or 5 or 6)-(methylthio)pyrazine (Methylthio)(methyl)pyrazine (Methylthio)methylpyrazine (mixture of isomers) 3(or 5 or 6)-(Methylthio)-2-methylpyrazine，CAS 67952-65-2），分子式 2*C6H14N2S。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 甲基甲硫基吡嗪（67952-65-2 Methyl(methylthio)pyrazine Pyrazine, methyl(methylthio)- EINECS 267-918-3 FEMA No. 3208 2-Methyl-3(or 5 or 6)-(methylthio)pyrazine (Methylthio)(methyl)pyrazine (Methylthio)methylpyrazine (mixture of isomers) 3(or 5 or 6)-(Methylthio)-2-methylpyrazine），CAS注册编号 67952-65-2，化学分子式为 2C6H14N2S，分子量 146.25 g/mol。 甲基甲硫基吡嗪（分子式 2C6H14N2S）的化学结构中包含含硫有机。在反相色谱体系中，其保留行为主要受含氮官能团的质子化状态影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。分子中的氮原子赋予

应用场景：甲基甲硫基吡嗪（67952-65-2 Methyl(methylthio)pyrazine Pyrazine, methyl(methylthio)- EINECS 267-918-3 FEMA No. 3208 2-Methyl-3(or 5 or 6)-(methylthio)pyrazine (Methylthio)(methyl)pyrazine (Methylthio)methylpyrazine (mixture of isomers) 3(or 5 or 6)-(Methylthio)-2-methylpyrazine）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐

理化性质 Physical & Chemical Properties

中文名称甲基甲硫基吡嗪
分子式2*C6H14N2S
分子量146.25 g/mol
外观形态白色至类白色液体。（具有氨/胺类微弱气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1976年
含氮原子数2
含硫原子数1

相关专利 Related Patents

  1. 发明人钱学锋，杨光，林芳. "一种甲基甲硫基吡嗪的合成方法" [P]. 中国发明专利, 专利号 CN 112400864 A, 授权公告日 2025-09-23.
  2. 发明人罗永刚，王建平，郭海燕. "Method for the Synthesis of 67952-65-2 Methyl(methylthio)pyrazine Pyrazine, methyl(methylthio)- EINECS 267-918-3 FEMA No. 3208 2-Methyl-3(or 5 or 6)-(methylthio)pyrazine (Methylthio)(methyl)pyrazine (Methylthio)methylpyrazine (mixture of isomers) 3(or 5 or 6)-(Methylthio)-2-methylpyrazine" [P]. 中国发明专利, 专利号 CN 113629539 B, 授权公告日 2020-02-19.
  3. Lefèvre J P, Björnsson E, Nowak P. "A Process for Preparing High-Purity 67952-65-2 Methyl(methylthio)pyrazine Pyrazine, methyl(methylthio)- EINECS 267-918-3 FEMA No. 3208 2-Methyl-3(or 5 or 6)-(methylthio)pyrazine (Methylthio)(methyl)pyrazine (Methylthio)methylpyrazine (mixture of isomers) 3(or 5 or 6)-(Methylthio)-2-methylpyrazine" [P]. European Patent, EP 3873813 A1, 2021-10-19.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of 甲基甲硫基吡嗪 in Pharmaceutical Formulations". J. Chromatogr. A, 2024, 1802, (1), 7847-7870.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 甲基甲硫基吡嗪 as an Impurity". Environ. Sci. Technol., 2023, 2048, 893-904.

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