ECOSURF<SUP>™</SUP> SA-4 CAS 68937-66-6

68937-66-6 Alcohols, C6-12, ethoxylated propoxylated (C6-C12) Alkyl alcohol ethoxylate propoxylate C6-C12 (Alkyl) alcohol ethoxylate propoxylate C6-C12 Alkyl alcohol ethoxylate propoxylate alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100

纯度 97%+现货药物标准品
CAS 号68937-66-6
分子式C9H20O C8H18O
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

ECOSURF<SUP>™</SUP> SA-4 68937-66-6 Alcohols, C6-12, ethoxylated propoxylated (C6-C12) Alkyl alcohol ethoxylate propoxylate C6-C12 (Alkyl) alcohol ethoxylate propoxylate C6-C12 Alkyl alcohol ethoxylate propoxylate alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100 CAS 68937-66-6 结构式 Chemical Structure

产品介绍 Description

ECOSURF<SUP>™</SUP> SA-4（68937-66-6 Alcohols, C6-12, ethoxylated propoxylated (C6-C12) Alkyl alcohol ethoxylate propoxylate C6-C12 (Alkyl) alcohol ethoxylate propoxylate C6-C12 Alkyl alcohol ethoxylate propoxylate alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100，CAS 号 68937-66-6）是 CATO 佳途自主生产的药物标准品，分子式 C9H20O C8H18O。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在质量保证方面，ECOSURF<SUP>™</SUP> SA-4的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 CAS编号 68937-66-6 对应的化合物ECOSURF<SUP>™</SUP> SA-4（英文标识 68937-66-6 Alcohols, C6-12, ethoxylated propoxylated (C6-C12) Alkyl alcohol ethoxylate propoxylate C6-C12 (Alkyl) alcohol ethoxylate propoxylate C6-C12 Alkyl alcohol ethoxylate propoxylate alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the al

应用场景：在化学分析实验室中，ECOSURF<SUP>™</SUP> SA-4（CAS 68937-66-6）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以ECOSURF<SUP>™</SUP> SA-4配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准

理化性质 Physical & Chemical Properties

中文名称ECOSURF<SUP>™</SUP> SA-4
分子式C9H20O C8H18O
分子量274.49 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-1.0
CAS登记年份（估）1976年

相关专利 Related Patents

  1. Jørgensen K, Lefèvre J P, Johansson L. "一种ECOSURF<SUP>™</SUP> SA-4的合成方法" [P]. European Patent, EP 3253534 A1, 2021-12-24.
  2. 发明人何建平，沈红梅，唐晓军. "Method for the Synthesis of 68937-66-6 Alcohols, C6-12, ethoxylated propoxylated (C6-C12) Alkyl alcohol ethoxylate propoxylate C6-C12 (Alkyl) alcohol ethoxylate propoxylate C6-C12 Alkyl alcohol ethoxylate propoxylate alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100" [P]. 中国发明专利, 专利号 CN 114617501 A, 授权公告日 2021-09-08.
  3. 发明人孙丽萍，冯建国，马晓峰. "A Process for Preparing High-Purity 68937-66-6 Alcohols, C6-12, ethoxylated propoxylated (C6-C12) Alkyl alcohol ethoxylate propoxylate C6-C12 (Alkyl) alcohol ethoxylate propoxylate C6-C12 Alkyl alcohol ethoxylate propoxylate alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100" [P]. 中国发明专利, 专利号 CN 116966178 B, 授权公告日 2016-07-18.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of ECOSURF<SUP>™</SUP> SA-4 in Pharmaceutical Formulations". J. Nat. Prod., 2012, 667, (6), 3434-3445.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of ECOSURF<SUP>™</SUP> SA-4 as an Impurity". Biomed. Chromatogr., 2010, 901, (6), 3542-3556.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of 68937-66-6 Alcohols, C6-12, ethoxylated propoxylated (C6-C12) Alkyl alcohol ethoxylate propoxylate C6-C12 (Alkyl) alcohol ethoxylate propoxylate C6-C12 Alkyl alcohol ethoxylate propoxylate alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100 Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2013, 525, (11), 6093-6107.
  4. Chen X Y, Liu M, Zhao W Q. "Forced Degradation Studies to Evaluate ECOSURF<SUP>™</SUP> SA-4 Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2019, 1017, 8519-8548.

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