1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐 CAS 70614-14-1

1,2-Dioleoyl-sn-glycero-3-phosphoserine 1,2-Dioleoylphosphatidylserine 1,2-Dlps 1,2-dioleoyl-sn-glycero-3-phospho-L-serine 70614-14-1 CHEBI:60568 DOPS DOPSE Dioleoyl phosphatidylserine O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine PS(18:1(9Z)/18:1(9Z)) PS(18:1/18:1) PS(18:1omega9/18:1omega9) PS(36:2) Phosphatidylserine(18:1/18:1) Phosphatidylserine(18:1omega9/18:1omega9) Phosphatidylserine(36:2)

纯度 97%+现货药物标准品
CAS 号70614-14-1
分子式C42H78NO10P
分子量788.04 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐 1,2-Dioleoyl-sn-glycero-3-phosphoserine 1,2-Dioleoylphosphatidylserine 1,2-Dlps 1,2-dioleoyl-sn-glycero-3-phospho-L-serine 70614-14-1 CHEBI:60568 DOPS DOPSE Dioleoyl phosphatidylserine O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine PS(18:1(9Z)/18:1(9Z)) PS(18:1/18:1) PS(18:1omega9/18:1omega9) PS(36:2) Phosphatidylserine(18:1/18:1) Phosphatidylserine(18:1omega9/18:1omega9) Phosphatidylserine(36:2) CAS 70614-14-1 结构式 Chemical Structure

产品介绍 Description

1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐（英文名 1,2-Dioleoyl-sn-glycero-3-phosphoserine 1,2-Dioleoylphosphatidylserine 1,2-Dlps 1,2-dioleoyl-sn-glycero-3-phospho-L-serine 70614-14-1 CHEBI:60568 DOPS DOPSE Dioleoyl phosphatidylserine O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine PS(18:1(9Z)/18:1(9Z)) PS(18:1/18:1) PS(18:1omega9/18:1omega9) PS(36:2) Phosphatidylserine(18:1/18:1) Phosphatidylserine(18:1omega9/18:1omega9) Phosphatidylserine(36:2)，CAS 70614-14-1）属于药物标准品。分子式 C42H78NO10P，分子量 788.04。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐在内的目标物的控制。 CAS编号 70614-14-1 对应的化合物1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐（英文标识 1,2-Dioleoyl-sn-glycero-3-phosphoserine 1,2-Dioleoylphosphatidylserine 1,2-Dlps 1,2-dioleoyl-sn-glycero-3-phospho-L-serine 70614-14-1 CHEBI:60568 DOPS DOPSE Dioleoyl phosphatidylserine O-({(2R)-2,3-bis(9Z)-octadec-9-enoyloxypropyl}oxy)(hydroxy)phosphoryl-L-serine PS(18:1(9Z)/18:1(9Z)) PS(18:1/18:1) PS(18:1omega9/18:1omega9) PS(36:2

应用场景：1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐（1,2-Dioleoyl-sn-glycero-3-phosphoserine 1,2-Dioleoylphosphatidylserine 1,2-Dlps 1,2-dioleoyl-sn-glycero-3-phospho-L-serine 70614-14-1 CHEBI:60568 DOPS DOPSE Dioleoyl phosphatidylserine O- ({(2R)-2,3-bis (9Z)-octadec-9-enoyloxy propyl}oxy)(hydroxy)phosph

理化性质 Physical & Chemical Properties

中文名称1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐
分子式C42H78NO10P
分子量788.04 g/mol
外观形态类白色至淡黄色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1977年
含氮原子数1

相关专利 Related Patents

  1. 发明人韩伟，朱建伟，唐晓军. "一种1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐的合成方法" [P]. 中国发明专利, 专利号 CN 113552386 A, 授权公告日 2023-01-26.
  2. Roberts E F, Park J H, Brown S R. "Method for the Synthesis of 1,2-Dioleoyl-sn-glycero-3-phosphoserine 1,2-Dioleoylphosphatidylserine 1,2-Dlps 1,2-dioleoyl-sn-glycero-3-phospho-L-serine 70614-14-1 CHEBI:60568 DOPS DOPSE Dioleoyl phosphatidylserine O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine PS(18:1(9Z)/18:1(9Z)) PS(18:1/18:1) PS(18:1omega9/18:1omega9) PS(36:2) Phosphatidylserine(18:1/18:1) Phosphatidylserine(18:1omega9/18:1omega9) Phosphatidylserine(36:2)" [P]. US Patent, US 10116583 B2, 2017-12-27.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐 in Pharmaceutical Formulations". Phytochemistry, 2013, 973, 9483-9498.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐 as an Impurity". Chromatographia, 2020, 1359, 3024-3053.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 1,2-Dioleoyl-sn-glycero-3-phosphoserine 1,2-Dioleoylphosphatidylserine 1,2-Dlps 1,2-dioleoyl-sn-glycero-3-phospho-L-serine 70614-14-1 CHEBI:60568 DOPS DOPSE Dioleoyl phosphatidylserine O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine PS(18:1(9Z)/18:1(9Z)) PS(18:1/18:1) PS(18:1omega9/18:1omega9) PS(36:2) Phosphatidylserine(18:1/18:1) Phosphatidylserine(18:1omega9/18:1omega9) Phosphatidylserine(36:2) Using HRMS and NMR". Anal. Methods, 2021, 2405, (7), 6625-6631.
  4. Brown R C, Davis S M. "Forced Degradation Studies to Evaluate 1,2-二油酰-<I> 锡 </I>-甘油-3-磷酸-<SC> L </SC>-丝氨酸 钠盐 Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2016, 2352, 811-824.

Related Dioleoyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...