C4 Ceramide (d18:1/4:0) CAS 74713-58-9

74713-58-9 SF3LP91341 Ceramide 4 UNII-SF3LP91341 Butanamide, N-((1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl)- Butanamide, N-(2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl)-, (R-(R*,S*-(E)))- Ceramide 4 (retired) [INCI] Ceramide as (ceramide 4) Ceramide as (ceramide 4) [INCI] N-Butyryl-D-erythro-sphingosine

纯度 97%+现货药物标准品
CAS 号74713-58-9
分子式C22H43NO3
分子量369.58 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

C4 Ceramide (d18:1/4:0) 74713-58-9 SF3LP91341 Ceramide 4 UNII-SF3LP91341 Butanamide, N-((1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl)- Butanamide, N-(2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl)-, (R-(R*,S*-(E)))- Ceramide 4 (retired) [INCI] Ceramide as (ceramide 4) Ceramide as (ceramide 4) [INCI] N-Butyryl-D-erythro-sphingosine CAS 74713-58-9 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品C4 Ceramide (d18:1/4:0)（74713-58-9 SF3LP91341 Ceramide 4 UNII-SF3LP91341 Butanamide, N-((1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl)- Butanamide, N-(2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl)-, (R-(R*,S*-(E)))- Ceramide 4 (retired) [INCI] Ceramide as (ceramide 4) Ceramide as (ceramide 4) [INCI] N-Butyryl-D-erythro-sphingosine，CAS 74713-58-9），分子式 C22H43NO3，分子量 369.58。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶剂：通过卡尔费休（KF）和热重分析（TGA）测定并校正； - 定值方法：HPLC-DAD面积归一化法、qNMR法、DSC法等正交验证； - 不确定度：扩展不确定度（k=2）包含测量重复性、均匀性和稳定性分量。 化学式为 C22H43NO3 的C4 Ceramide (d18:1/4:0)（74713-58-9 SF3LP91341 Ceramide 4 UNII-SF3LP91341 Butanamide, N-((1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl)- Butanamide, N-(2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl)-, (R-(R,S-(E)))- Ceramide 4 (retired) INCI Ceramide as (ceramide 4) Ceramide as (ceramide 4) INCI N-Butyryl-D-

应用场景：C4 Ceramide (d18:1/4:0)（74713-58-9 SF3LP91341 Ceramide 4 UNII-SF3LP91341 Butanamide, N-((1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl)- Butanamide, N-(2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl)-, (R-(R ,S -(E)))- Ceramide 4 (retired) INCI Ceramide as (ceramide 4) Ceramide as (ceramide

理化性质 Physical & Chemical Properties

中文名称C4 Ceramide (d18:1/4:0)
分子式C22H43NO3
分子量369.58 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1978年
含氮原子数1

相关专利 Related Patents

  1. 发明人高志强，孙丽萍，黄志刚. "一种C4 Ceramide (d18:1/4:0)的合成方法" [P]. 中国发明专利, 专利号 CN 108052672 A, 授权公告日 2015-04-26.
  2. 发明人马晓峰，陈志强，冯建国. "Method for the Synthesis of 74713-58-9 SF3LP91341 Ceramide 4 UNII-SF3LP91341 Butanamide, N-((1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl)- Butanamide, N-(2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl)-, (R-(R*,S*-(E)))- Ceramide 4 (retired) [INCI] Ceramide as (ceramide 4) Ceramide as (ceramide 4) [INCI] N-Butyryl-D-erythro-sphingosine" [P]. 中国发明专利, 专利号 CN 114235848 B, 授权公告日 2015-12-08.
  3. 发明人罗永刚，赵玉洁，林芳. "A Process for Preparing High-Purity 74713-58-9 SF3LP91341 Ceramide 4 UNII-SF3LP91341 Butanamide, N-((1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl)- Butanamide, N-(2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl)-, (R-(R*,S*-(E)))- Ceramide 4 (retired) [INCI] Ceramide as (ceramide 4) Ceramide as (ceramide 4) [INCI] N-Butyryl-D-erythro-sphingosine" [P]. 中国发明专利, 专利号 CN 117815728 A, 授权公告日 2020-05-19.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of C4 Ceramide (d18:1/4:0) in Pharmaceutical Formulations". J. Chromatogr. A, 2025, 807, 9550-9553.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of C4 Ceramide (d18:1/4:0) as an Impurity". Sci. Total Environ., 2018, 1897, (4), 5933-5961.

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