N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide CAS 748776-69-4

N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide

纯度 97%+现货药物标准品
CAS 号748776-69-4
分子式C16H24N4O3S2
分子量384.52 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide CAS 748776-69-4 结构式 Chemical Structure

产品介绍 Description

N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide（N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide，CAS 号 748776-69-4）是 CATO 佳途自主生产的药物标准品，分子式 C16H24N4O3S2，分子量 384.52。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

与同类药物标准品相比，N,N-Diethyl-3-5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-1,2,4triazol-3-yl-benzenesulfonamide的分子量为384.52 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C16H24N4O3S2 的N,N-Diethyl-3-5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-1,2,4triazol-3-yl-benzenesulfonamide（N,N-Diethyl-3-5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-1,2,4triazol-3-yl-benzenesulfonamide），其CAS登记号是 748776-69-4，分子量为 384.52 g/mol。 N,N-Diethyl-3-5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-1,2,4triazol-3-yl-benzenes

应用场景：针对化学分析用途，N,N-Diethyl-3- 5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H- 1,2,4 triazol-3-yl -benzenesulfonamide（N,N-Diethyl-3- 5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H- 1,2,4 triazol-3-yl -benzenesulfonamide）是具有明确定量溯源的认证级对照品。 推荐以N,N-Diethyl-3- 5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H- 1,2,4 triazol-

理化性质 Physical & Chemical Properties

中文名称N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide
分子式C16H24N4O3S2
分子量384.52 g/mol
外观形态类白色至淡黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1986年
含氮原子数4
含硫原子数2

相关专利 Related Patents

  1. 发明人周伟，沈红梅，刘建华. "一种N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide的合成方法" [P]. 中国发明专利, 专利号 CN 110815670 A, 授权公告日 2019-06-28.
  2. Roberts E F, Park J H, Anderson J P. "Method for the Synthesis of N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide" [P]. US Patent, US 11829594 B2, 2023-05-22.
  3. 发明人黄志刚，李文辉，何建平. "A Process for Preparing High-Purity N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide" [P]. 中国发明专利, 专利号 CN 108907071 A, 授权公告日 2022-03-15.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide in Pharmaceutical Formulations". J. Sep. Sci., 2010, 683, (12), 5769-5788.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide as an Impurity". J. Agric. Food Chem., 2010, 2053, 7449-7459.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide Using HRMS and NMR". Environ. Sci. Technol., 2011, 99, (12), 212-218.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate N,N-Diethyl-3-[5-mercapto-4-(2-methoxy-1-methyl-ethyl)-4H-[1,2,4]triazol-3-yl]-benzenesulfonamide Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2014, 1660, (7), 802-817.

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