甲基三氯硅烷 CAS 75-79-6
75-79-6 UIR5I18638 Methyltrichlorosilane Silane, methyltrichloro- Silane, trichloromethyl- Trichloro(methyl)silane 4-04-00-04212 (Beilstein Handbook Reference) AI3-51465 BRN 1361381 CCRIS 1322 EINECS 200-902-6 HSDB 840 Methylsilicochloroform Methylsilyl trichloride Methyl-trichlorsilan [Czech] Monomethyltrichlorosilane NSC 77069 Trichlor-methylsilan [Czech] Trichloromethylsilane Trichloromethylsilicon Methyl-trichlorsilan Trichlor-methylsilan UNII-UIR5I18638 EC 200-902-6 Methyltrichlorosilane [UN1250] [Flammable liquid] UN1250
| CAS 号 | 75-79-6 |
| 分子式 | CH3Cl3Si |
| 分子量 | 149.48 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
甲基三氯硅烷（英文名 75-79-6 UIR5I18638 Methyltrichlorosilane Silane, methyltrichloro- Silane, trichloromethyl- Trichloro(methyl)silane 4-04-00-04212 (Beilstein Handbook Reference) AI3-51465 BRN 1361381 CCRIS 1322 EINECS 200-902-6 HSDB 840 Methylsilicochloroform Methylsilyl trichloride Methyl-trichlorsilan [Czech] Monomethyltrichlorosilane NSC 77069 Trichlor-methylsilan [Czech] Trichloromethylsilane Trichloromethylsilicon Methyl-trichlorsilan Trichlor-methylsilan UNII-UIR5I18638 EC 200-902-6 Methyltrichlorosilane [UN1250] [Flammable liquid] UN1250，CAS 75-79-6）属于药物标准品。分子式 CH3Cl3Si，分子量 149.48。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
甲基三氯硅烷的产生途径与其化学式中含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 CH3Cl3Si 的甲基三氯硅烷（75-79-6 UIR5I18638 Methyltrichlorosilane Silane, methyltrichloro- Silane, trichloromethyl- Trichloro(methyl)silane 4-04-00-04212 (Beilstein Handbook Reference) AI3-51465 BRN 1361381 CCRIS 1322 EINECS 200-902-6 HSDB 840 Methylsilicochloroform Methylsilyl trichloride Methyl-trichlorsilan Czech Monomethyltrichlorosilane NSC 77069 Trichlor-methylsilan Czech Trichloromethylsilane Trichloromethylsilicon Methyl-trichlor
应用场景：甲基三氯硅烷（75-79-6 UIR5I18638 Methyltrichlorosilane Silane, methyltrichloro- Silane, trichloromethyl- Trichloro(methyl)silane 4-04-00-04212 (Beilstein Handbook Reference) AI3-51465 BRN 1361381 CCRIS 1322 EINECS 200-902-6 HSDB 840 Methylsilicochloroform Methylsilyl trichloride Methyl-trichlorsilan Czech
理化性质 Physical & Chemical Properties
| 中文名称 | 甲基三氯硅烷 |
| 分子式 | CH3Cl3Si |
| 分子量 | 149.48 g/mol |
| 外观形态 | 白色至类白色液体。（具有轻微卤代物特征气味，挥发性较低） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，密闭保存防止挥发 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO |
| 稳定性 | 在推荐条件下性质稳定 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | -1.0 |
| CAS登记年份（估） | 1957年 |
| 卤素含量 | Cl取代 |
相关专利 Related Patents
- 发明人李文辉，黄志刚，林芳. "一种甲基三氯硅烷的合成方法" [P]. 中国发明专利, 专利号 CN 117099766 B, 授权公告日 2016-06-22.
- 发明人罗永刚，徐明华，高志强. "Method for the Synthesis of 75-79-6 UIR5I18638 Methyltrichlorosilane Silane, methyltrichloro- Silane, trichloromethyl- Trichloro(methyl)silane 4-04-00-04212 (Beilstein Handbook Reference) AI3-51465 BRN 1361381 CCRIS 1322 EINECS 200-902-6 HSDB 840 Methylsilicochloroform Methylsilyl trichloride Methyl-trichlorsilan [Czech] Monomethyltrichlorosilane NSC 77069 Trichlor-methylsilan [Czech] Trichloromethylsilane Trichloromethylsilicon Methyl-trichlorsilan Trichlor-methylsilan UNII-UIR5I18638 EC 200-902-6 Methyltrichlorosilane [UN1250] [Flammable liquid] UN1250" [P]. 中国发明专利, 专利号 CN 116728256 A, 授权公告日 2019-02-10.
- 发明人杨光，钱学锋，高志强. "A Process for Preparing High-Purity 75-79-6 UIR5I18638 Methyltrichlorosilane Silane, methyltrichloro- Silane, trichloromethyl- Trichloro(methyl)silane 4-04-00-04212 (Beilstein Handbook Reference) AI3-51465 BRN 1361381 CCRIS 1322 EINECS 200-902-6 HSDB 840 Methylsilicochloroform Methylsilyl trichloride Methyl-trichlorsilan [Czech] Monomethyltrichlorosilane NSC 77069 Trichlor-methylsilan [Czech] Trichloromethylsilane Trichloromethylsilicon Methyl-trichlorsilan Trichlor-methylsilan UNII-UIR5I18638 EC 200-902-6 Methyltrichlorosilane [UN1250] [Flammable liquid] UN1250" [P]. 中国发明专利, 专利号 CN 113142943 B, 授权公告日 2018-04-12.
参考文献 Literature
- Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 甲基三氯硅烷 in Pharmaceutical Formulations". Environ. Sci. Technol., 2013, 1245, (2), 3751-3772.
- Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 甲基三氯硅烷 as an Impurity". Food Chem., 2022, 1833, 6969-6978.
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