14:0-18:0 PC CAS 76343-22-1

76343-22-1 1-Myristoyl-2-stearoylphosphatidylcholine 3,5,8-Trioxa-4-phosphahexacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-, hydroxide, inner salt, 4-oxide, (R)- 4-Hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-3,5,8-trioxa-4-phosphahexacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)- 1M-2S-PC

纯度 97%+现货药物标准品
CAS 号76343-22-1
分子式C40H80NO8P
分子量734.04 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

14:0-18:0 PC 76343-22-1 1-Myristoyl-2-stearoylphosphatidylcholine 3,5,8-Trioxa-4-phosphahexacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-, hydroxide, inner salt, 4-oxide, (R)- 4-Hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-3,5,8-trioxa-4-phosphahexacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)- 1M-2S-PC CAS 76343-22-1 结构式 Chemical Structure

产品介绍 Description

CAS 76343-22-1 对应的14:0-18:0 PC（76343-22-1 1-Myristoyl-2-stearoylphosphatidylcholine 3,5,8-Trioxa-4-phosphahexacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-, hydroxide, inner salt, 4-oxide, (R)- 4-Hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-3,5,8-trioxa-4-phosphahexacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)- 1M-2S-PC）为 CATO 佳途药物标准品产品线成员。分子式 C40H80NO8P，分子量 734.04。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

CAS编号 76343-22-1 对应的化合物14:0-18:0 PC（英文标识 76343-22-1 1-Myristoyl-2-stearoylphosphatidylcholine 3,5,8-Trioxa-4-phosphahexacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-, hydroxide, inner salt, 4-oxide, (R)- 4-Hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-3,5,8-trioxa-4-phosphahexacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)- 1M-2S-PC），化学式 C40H80NO8P，相对分子质量 734.04。 14:0-18:0 PC（分子式 C40H80NO8P）的化学结构中包含酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键。在反相色谱体系中，其保留行为主要

应用场景：14:0-18:0 PC（76343-22-1 1-Myristoyl-2-stearoylphosphatidylcholine 3,5,8-Trioxa-4-phosphahexacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-, hydroxide, inner salt, 4-oxide, (R)- 4-Hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-3,5,8-trioxa-4-phospha

理化性质 Physical & Chemical Properties

中文名称14:0-18:0 PC
分子式C40H80NO8P
分子量734.04 g/mol
外观形态白色至类白色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）1978年
含氮原子数1

相关专利 Related Patents

  1. 发明人张德明，徐明华，刘建华. "一种14:0-18:0 PC的合成方法" [P]. 中国发明专利, 专利号 CN 113656801 B, 授权公告日 2020-09-19.
  2. Davis P L, Anderson J P, Mueller T. "Method for the Synthesis of 76343-22-1 1-Myristoyl-2-stearoylphosphatidylcholine 3,5,8-Trioxa-4-phosphahexacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-, hydroxide, inner salt, 4-oxide, (R)- 4-Hydroxy-N,N,N-trimethyl-9-oxo-7-(((1-oxotetradecyl)oxy)methyl)-3,5,8-trioxa-4-phosphahexacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)- 1M-2S-PC" [P]. US Patent, US 10334671 B2, 2024-09-13.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 14:0-18:0 PC in Pharmaceutical Formulations". Biomed. Chromatogr., 2019, 976, (5), 5653-5677.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of 14:0-18:0 PC as an Impurity". Chemosphere, 2013, 2422, (5), 2182-2208.

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