PIPES 二钠盐 CAS 76836-02-7

76836-02-7 O25162TU3U PIPES disodium salt Disodium piperazine-1,4-diethanesulphonate 1,4-Piperazinediethanesulfonic acid, sodium salt (1:2) 1,4-Piperazinediethanesulfonic acid, disodium salt EINECS 278-562-3 Piperazine, N,N'-bis(2-ethanesulfonic acid) disodium salt UNII-O25162TU3U

纯度 97%+现货药物标准品
CAS 号76836-02-7
分子式C8H16N2O6S2 2*Na
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

PIPES 二钠盐 76836-02-7 O25162TU3U PIPES disodium salt Disodium piperazine-1,4-diethanesulphonate 1,4-Piperazinediethanesulfonic acid, sodium salt (1:2) 1,4-Piperazinediethanesulfonic acid, disodium salt EINECS 278-562-3 Piperazine, N,N'-bis(2-ethanesulfonic acid) disodium salt UNII-O25162TU3U CAS 76836-02-7 结构式 Chemical Structure

产品介绍 Description

PIPES 二钠盐（76836-02-7 O25162TU3U PIPES disodium salt Disodium piperazine-1,4-diethanesulphonate 1,4-Piperazinediethanesulfonic acid, sodium salt (1:2) 1,4-Piperazinediethanesulfonic acid, disodium salt EINECS 278-562-3 Piperazine, N,N'-bis(2-ethanesulfonic acid) disodium salt UNII-O25162TU3U）是药物分析与质量控制领域常用的药物标准品，CAS 号 76836-02-7。分子式 C8H16N2O6S2 2*Na。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在质量保证方面，PIPES 二钠盐的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 PIPES 二钠盐（76836-02-7 O25162TU3U PIPES disodium salt Disodium piperazine-1,4-diethanesulphonate 1,4-Piperazinediethanesulfonic acid, sodium salt (1:2) 1,4-Piperazinediethanesulfonic acid, disodium salt EINECS 278-562-3 Piperazine, N,N'-bis(2-ethanesulfonic acid) disodium salt UNII-O25162TU3U），CAS注册编号 76836-02-7，化学分子式为 C8H16N2O6S2 2Na，分子量 323.33

应用场景：PIPES 二钠盐（76836-02-7 O25162TU3U PIPES disodium salt Disodium piperazine-1,4-diethanesulphonate 1,4-Piperazinediethanesulfonic acid, sodium salt (1:2) 1,4-Piperazinediethanesulfonic acid, disodium salt EINECS 278-562-3 Piperazine, N,N'-bis(2-ethanesulfonic acid) disodium salt UNII-O25162TU3U）作为药物标准品，

理化性质 Physical & Chemical Properties

中文名称PIPES 二钠盐
分子式C8H16N2O6S2 2*Na
分子量323.33 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1978年
含氮原子数2
含硫原子数2

相关专利 Related Patents

  1. Johansson L, Björnsson E, Martínez F. "一种PIPES 二钠盐的合成方法" [P]. European Patent, EP 3785123 A1, 2024-04-25.
  2. Thompson G K, Davis P L, Park J H. "Method for the Synthesis of 76836-02-7 O25162TU3U PIPES disodium salt Disodium piperazine-1,4-diethanesulphonate 1,4-Piperazinediethanesulfonic acid, sodium salt (1:2) 1,4-Piperazinediethanesulfonic acid, disodium salt EINECS 278-562-3 Piperazine, N,N'-bis(2-ethanesulfonic acid) disodium salt UNII-O25162TU3U" [P]. US Patent, US 9845875 B2, 2024-05-09.
  3. 发明人郑宇鹏，王建平，赵玉洁. "A Process for Preparing High-Purity 76836-02-7 O25162TU3U PIPES disodium salt Disodium piperazine-1,4-diethanesulphonate 1,4-Piperazinediethanesulfonic acid, sodium salt (1:2) 1,4-Piperazinediethanesulfonic acid, disodium salt EINECS 278-562-3 Piperazine, N,N'-bis(2-ethanesulfonic acid) disodium salt UNII-O25162TU3U" [P]. 中国发明专利, 专利号 CN 109338019 B, 授权公告日 2017-02-19.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of PIPES 二钠盐 in Pharmaceutical Formulations". J. Sep. Sci., 2013, 1766, 8953-8966.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of PIPES 二钠盐 as an Impurity". Rapid Commun. Mass Spectrom., 2025, 595, 5039-5046.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of 76836-02-7 O25162TU3U PIPES disodium salt Disodium piperazine-1,4-diethanesulphonate 1,4-Piperazinediethanesulfonic acid, sodium salt (1:2) 1,4-Piperazinediethanesulfonic acid, disodium salt EINECS 278-562-3 Piperazine, N,N'-bis(2-ethanesulfonic acid) disodium salt UNII-O25162TU3U Using HRMS and NMR". J. Agric. Food Chem., 2017, 289, 8980-8985.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate PIPES 二钠盐 Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2011, 839, 6760-6766.

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