2-氨基吡啶-5-硼酸频哪醇酯 CAS 827614-64-2

2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-aminopyridine-5-boronic acid, pinacol ester 2-aminopyridine-5-boronic acid pinacol ester 6-aminopyridine-3-boronic acid pinacol ester 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-ylamine 2-aminopyridine-5-boronic acid,pinacol ester 827614-64-2

纯度 97%+现货药物标准品
CAS 号827614-64-2
分子式C11H23BN2O2
分子量226.12 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-氨基吡啶-5-硼酸频哪醇酯 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-aminopyridine-5-boronic acid, pinacol ester 2-aminopyridine-5-boronic acid pinacol ester 6-aminopyridine-3-boronic acid pinacol ester 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-ylamine 2-aminopyridine-5-boronic acid,pinacol ester 827614-64-2 CAS 827614-64-2 结构式 Chemical Structure

产品介绍 Description

CAS 827614-64-2 对应的2-氨基吡啶-5-硼酸频哪醇酯（2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-aminopyridine-5-boronic acid, pinacol ester 2-aminopyridine-5-boronic acid pinacol ester 6-aminopyridine-3-boronic acid pinacol ester 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-ylamine 2-aminopyridine-5-boronic acid,pinacol ester 827614-64-2）为 CATO 佳途药物标准品产品线成员。分子式 C11H23BN2O2，分子量 226.12。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

与同类药物标准品相比，2-氨基吡啶-5-硼酸频哪醇酯的分子量为226.12 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 2-氨基吡啶-5-硼酸频哪醇酯（2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-aminopyridine-5-boronic acid, pinacol ester 2-aminopyridine-5-boronic acid pinacol ester 6-aminopyridine-3-boronic acid pinacol ester 5-(4,4,5,5-tetramethyl-1,3,2dioxaborolan-2-yl)-pyridin-2-ylamine 2-aminopyridine-5-boronic acid,pinacol ester 827614-64-2），CAS注册编号 827614-64-2，化学分子式为 C11H23BN2O2，分子量 226.12 g/mol。 2-氨基吡啶-5-硼酸频哪醇酯（C11H23BN2O2

应用场景：2-氨基吡啶-5-硼酸频哪醇酯（2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-aminopyridine-5-boronic acid, pinacol ester 2-aminopyridine-5-boronic acid pinacol ester 6-aminopyridine-3-boronic acid pinacol ester 5-(4,4,5,5-tetramethyl- 1,3,2 dioxaborolan-2-yl)-pyridin-2-ylamine 2-aminopyridine-5

理化性质 Physical & Chemical Properties

中文名称2-氨基吡啶-5-硼酸频哪醇酯
分子式C11H23BN2O2
分子量226.12 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）1986年
含氮原子数2

相关专利 Related Patents

  1. Roberts E F, O'Brien P Q, Park J H. "一种2-氨基吡啶-5-硼酸频哪醇酯的合成方法" [P]. US Patent, US 11725752 B2, 2021-05-09.
  2. Anderson J P, Williams B T, Kumar R. "Method for the Synthesis of 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-aminopyridine-5-boronic acid, pinacol ester 2-aminopyridine-5-boronic acid pinacol ester 6-aminopyridine-3-boronic acid pinacol ester 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-ylamine 2-aminopyridine-5-boronic acid,pinacol ester 827614-64-2" [P]. US Patent, US 9969663 B2, 2024-12-22.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 2-氨基吡啶-5-硼酸频哪醇酯 in Pharmaceutical Formulations". Chemosphere, 2012, 2471, (5), 7550-7561.
  2. Yang F, Sun W, Liu J. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-氨基吡啶-5-硼酸频哪醇酯 as an Impurity". J. Nat. Prod., 2025, 1951, 4135-4158.

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