2-naphthol-6-sulfonic acid potassium salt CAS 833-66-9

833-66-9 4IDS1OY3TA Potassium 6-hydroxy-2-naphthalenesulfonate Potassium 6-hydroxynaphthalene-2-sulphonate 2-Naphthalenesulfonic acid, 6-hydroxy-, potassium salt (1:1) 2-Naphthalenesulfonic acid, 6-hydroxy-, monopotassium salt EINECS 212-631-0 Schaeffer's acid, monopotassium salt UNII-4IDS1OY3TA

纯度 97%+现货药物标准品
CAS 号833-66-9
分子式C10H17O4S K
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-naphthol-6-sulfonic acid potassium salt 833-66-9 4IDS1OY3TA Potassium 6-hydroxy-2-naphthalenesulfonate Potassium 6-hydroxynaphthalene-2-sulphonate 2-Naphthalenesulfonic acid, 6-hydroxy-, potassium salt (1:1) 2-Naphthalenesulfonic acid, 6-hydroxy-, monopotassium salt EINECS 212-631-0 Schaeffer's acid, monopotassium salt UNII-4IDS1OY3TA CAS 833-66-9 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品2-naphthol-6-sulfonic acid potassium salt（833-66-9 4IDS1OY3TA Potassium 6-hydroxy-2-naphthalenesulfonate Potassium 6-hydroxynaphthalene-2-sulphonate 2-Naphthalenesulfonic acid, 6-hydroxy-, potassium salt (1:1) 2-Naphthalenesulfonic acid, 6-hydroxy-, monopotassium salt EINECS 212-631-0 Schaeffer's acid, monopotassium salt UNII-4IDS1OY3TA，CAS 833-66-9），分子式 C10H17O4S K。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

从化学结构特征来看，2-naphthol-6-sulfonic acid potassium salt的分子骨架中包含含砜基，羧酸类，含羟基，含醚键。该化合物的不饱和度为2.5，表明结构中存在约2个环或双键等价单元。分子量为272.40 g/mol，属于中等分子量化合物。由于碳链较长，脂溶性良好，该化合物在Octanol-Water分配系数测试中倾向于有机相。 CAS编号 833-66-9 对应的化合物2-naphthol-6-sulfonic acid potassium salt（英文标识 833-66-9 4IDS1OY3TA Potassium 6-hydroxy-2-naphthalenesulfonate Potassium 6-hydroxynaphthalene-2-sulphonate 2-Naphthalenesulfonic acid, 6-hydroxy-, potassium salt (1:1) 2-Naphthalenesulfonic acid, 6-hydroxy-, monopotassium salt EINECS 212-631-0 Schae

应用场景：从实际应用出发，2-naphthol-6-sulfonic acid potassium salt（CAS 833-66-9）在化学分析中作为关键的基准对照物质。 推荐以2-naphthol-6-sulfonic acid potassium salt配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于阴凉处（≤25°C）保存，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； -

理化性质 Physical & Chemical Properties

中文名称2-naphthol-6-sulfonic acid potassium salt
分子式C10H17O4S K
分子量272.40 g/mol
外观形态白色至类白色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.5
CAS登记年份（估）1957年
含硫原子数1

相关专利 Related Patents

  1. Rossi M, Sørensen M, Lefèvre J P. "一种2-naphthol-6-sulfonic acid potassium salt的合成方法" [P]. European Patent, EP 3492436 A1, 2016-04-08.
  2. 发明人徐明华，杨光，孙丽萍. "Method for the Synthesis of 833-66-9 4IDS1OY3TA Potassium 6-hydroxy-2-naphthalenesulfonate Potassium 6-hydroxynaphthalene-2-sulphonate 2-Naphthalenesulfonic acid, 6-hydroxy-, potassium salt (1:1) 2-Naphthalenesulfonic acid, 6-hydroxy-, monopotassium salt EINECS 212-631-0 Schaeffer's acid, monopotassium salt UNII-4IDS1OY3TA" [P]. 中国发明专利, 专利号 CN 109602548 B, 授权公告日 2025-10-27.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of 2-naphthol-6-sulfonic acid potassium salt in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2019, 194, 9981-9989.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-naphthol-6-sulfonic acid potassium salt as an Impurity". Talanta, 2015, 1103, 920-947.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of 833-66-9 4IDS1OY3TA Potassium 6-hydroxy-2-naphthalenesulfonate Potassium 6-hydroxynaphthalene-2-sulphonate 2-Naphthalenesulfonic acid, 6-hydroxy-, potassium salt (1:1) 2-Naphthalenesulfonic acid, 6-hydroxy-, monopotassium salt EINECS 212-631-0 Schaeffer's acid, monopotassium salt UNII-4IDS1OY3TA Using HRMS and NMR". J. Agric. Food Chem., 2013, 304, (2), 35-55.

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