PHA 767491 hydrochloride CAS 845538-12-7

1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride 845538-12-7 PHA 767491 hydrochloride PHA-00767491 hydrochloride

纯度 97%+现货药物标准品
CAS 号845538-12-7
分子式C12H21N3O HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

PHA 767491 hydrochloride 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride 845538-12-7 PHA 767491 hydrochloride PHA-00767491 hydrochloride CAS 845538-12-7 结构式 Chemical Structure

产品介绍 Description

PHA 767491 hydrochloride（1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride 845538-12-7 PHA 767491 hydrochloride PHA-00767491 hydrochloride，CAS 号 845538-12-7）是 CATO 佳途自主生产的药物标准品，分子式 C12H21N3O HCl。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

与同类药物标准品相比，PHA 767491 hydrochloride的分子量为259.78 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 PHA 767491 hydrochloride（1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo3,2-cpyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo3,2-cpyridin-4-one hydrochloride 845538-12-7 PHA 767491 hydrochloride PHA-00767491 hydrochloride），CAS注册编号 845538-12-7，化学分子式为 C12H21N3O HCl，分子量 259.78 g/mol。 依据分子式为 C12H21N3O HCl 的PHA 767491 hydrochloride结构特征，其分子内含酰胺类，含羟基，含醚键，含氯取代，这意味着该化合物在紫外光谱中会呈现特征性的吸收带。分子量 259.78 g/

应用场景：针对化学分析用途，PHA 767491 hydrochloride（1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo 3,2-c pyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo 3,2-c pyridin-4-one hydrochloride 845538-12-7 PHA 767491 hydrochloride PHA-00767491 hydrochloride）是具有明确定量溯源的认证级对照品。 推荐以PHA 767491 hydrochloride

理化性质 Physical & Chemical Properties

中文名称PHA 767491 hydrochloride
分子式C12H21N3O HCl
分子量259.78 g/mol
外观形态白色至淡黄色低熔点固体。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1987年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. 发明人马晓峰，郭海燕，刘建华. "一种PHA 767491 hydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 112843983 A, 授权公告日 2023-04-10.
  2. Lee S K, O'Brien P Q, Johnson M A. "Method for the Synthesis of 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride 845538-12-7 PHA 767491 hydrochloride PHA-00767491 hydrochloride" [P]. US Patent, US 10208491 B2, 2022-05-20.
  3. 发明人杨光，何建平，赵玉洁. "A Process for Preparing High-Purity 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride 845538-12-7 PHA 767491 hydrochloride PHA-00767491 hydrochloride" [P]. 中国发明专利, 专利号 CN 109811385 B, 授权公告日 2019-02-10.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of PHA 767491 hydrochloride in Pharmaceutical Formulations". Anal. Chim. Acta, 2025, 248, (5), 2137-2155.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of PHA 767491 hydrochloride as an Impurity". Talanta, 2019, 477, (7), 152-171.
  3. Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride 845538-12-7 PHA 767491 hydrochloride PHA-00767491 hydrochloride Using HRMS and NMR". Sci. Total Environ., 2016, 2360, (3), 8928-8939.

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