Me <I> 4 </I>叔丁基磷 CAS 857356-94-6
2-Di-t-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-tri-i-propylbiphenyl 857356-94-6 2-DI-T-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRI-I-PROPYLBIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYL-1,1'-BIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYLBIPHENYL;DI-TERT-BUTYL(2',4',6'-TRIISOPROPYL-3,4,5,6-TETRAMETHYL-[1,1'-BIPHENYL]-2-YL)PHOSPHINE;ME4 T-BUTYLXPHOS;TETRAMETHYL DI-TBUXPHOS SC11287
| CAS 号 | 857356-94-6 |
| 分子式 | C33H65P |
| 分子量 | 492.84 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CATO 佳途供应的Me <I> 4 </I>叔丁基磷（2-Di-t-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-tri-i-propylbiphenyl 857356-94-6 2-DI-T-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRI-I-PROPYLBIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYL-1,1'-BIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYLBIPHENYL;DI-TERT-BUTYL(2',4',6'-TRIISOPROPYL-3,4,5,6-TETRAMETHYL-[1,1'-BIPHENYL]-2-YL)PHOSPHINE;ME4 T-BUTYLXPHOS;TETRAMETHYL DI-TBUXPHOS SC11287）为药物标准品，CAS 登记号 857356-94-6，分子式 C33H65P，分子量 492.84。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。
在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括Me <I> 4 </I>叔丁基磷在内的目标物的控制。 CAS编号 857356-94-6 对应的化合物Me <I> 4 </I>叔丁基磷（英文标识 2-Di-t-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-tri-i-propylbiphenyl 857356-94-6 2-DI-T-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRI-I-PROPYLBIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYL-1,1'-BIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYLBIPHENYL;DI-TERT-BUTYL(2',4',6'-TRIISOPROPYL-3,4,5,6-TETRAMETHYL-1,1'-BIPHENYL-2-YL)PHOSP
应用场景：Me <I> 4 </I>叔丁基磷（2-Di-t-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-tri-i-propylbiphenyl 857356-94-6 2-DI-T-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRI-I-PROPYLBIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYL-1,1'-BIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-
理化性质 Physical & Chemical Properties
| 中文名称 | Me <I> 4 </I>叔丁基磷 |
| 分子式 | C33H65P |
| 分子量 | 492.84 g/mol |
| 外观形态 | 白色至类白色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 室温保存 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯 |
| 稳定性 | 在推荐条件下性质稳定 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.5 |
| CAS登记年份（估） | 1987年 |
相关专利 Related Patents
- Yamamoto T, Fischer A B, O'Brien P Q. "一种Me <I> 4 </I>叔丁基磷的合成方法" [P]. US Patent, US 11562803 B2, 2023-02-21.
- 发明人杨光，沈红梅，赵玉洁. "Method for the Synthesis of 2-Di-t-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-tri-i-propylbiphenyl 857356-94-6 2-DI-T-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRI-I-PROPYLBIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYL-1,1'-BIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYLBIPHENYL;DI-TERT-BUTYL(2',4',6'-TRIISOPROPYL-3,4,5,6-TETRAMETHYL-[1,1'-BIPHENYL]-2-YL)PHOSPHINE;ME4 T-BUTYLXPHOS;TETRAMETHYL DI-TBUXPHOS SC11287" [P]. 中国发明专利, 专利号 CN 111330933 B, 授权公告日 2018-01-23.
- 发明人高志强，马晓峰，张德明. "A Process for Preparing High-Purity 2-Di-t-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-tri-i-propylbiphenyl 857356-94-6 2-DI-T-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRI-I-PROPYLBIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYL-1,1'-BIPHENYL;2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAMETHYL-2',4',6'-TRIISOPROPYLBIPHENYL;DI-TERT-BUTYL(2',4',6'-TRIISOPROPYL-3,4,5,6-TETRAMETHYL-[1,1'-BIPHENYL]-2-YL)PHOSPHINE;ME4 T-BUTYLXPHOS;TETRAMETHYL DI-TBUXPHOS SC11287" [P]. 中国发明专利, 专利号 CN 108780655 A, 授权公告日 2024-09-17.
参考文献 Literature
- Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of Me <I> 4 </I>叔丁基磷 in Pharmaceutical Formulations". Talanta, 2012, 159, (8), 9077-9084.
- Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of Me <I> 4 </I>叔丁基磷 as an Impurity". Environ. Sci. Technol., 2015, 1409, 1263-1284.
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