香草醛-甲氧基-<SUP>13</SUP>C CAS 86884-84-6
2-(Methoxy-13C)-4-formylphenol 3-(Methoxy-13C)-4-hydroxybenzaldehyde 4-Formyl-2-(methoxy-13C)phenol 4-Hydroxy-3-(methoxy-13C)benzaldehyde 4-Hydroxy-3-methoxy-13C-benzaldehyde 4-Hydroxy-m-anisaldehyde-13C 86884-84-6 H 0264-13C Lioxin-13C NSC 15351-13C NSC 403658-13C Rhovanil-13C Vanillaldehyde-13C Vanillic Aldehyde-13C Vanillin-(methoxy-13C) Vanillin-13C p-Vanillin-13C
| CAS 号 | 86884-84-6 |
| 分子式 | C7[13C]H14O3 |
| 分子量 | 159.19 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CAS 86884-84-6 对应的香草醛-甲氧基-<SUP>13</SUP>C（2-(Methoxy-13C)-4-formylphenol 3-(Methoxy-13C)-4-hydroxybenzaldehyde 4-Formyl-2-(methoxy-13C)phenol 4-Hydroxy-3-(methoxy-13C)benzaldehyde 4-Hydroxy-3-methoxy-13C-benzaldehyde 4-Hydroxy-m-anisaldehyde-13C 86884-84-6 H 0264-13C Lioxin-13C NSC 15351-13C NSC 403658-13C Rhovanil-13C Vanillaldehyde-13C Vanillic Aldehyde-13C Vanillin-(methoxy-13C) Vanillin-13C p-Vanillin-13C）为 CATO 佳途药物标准品产品线成员。分子式 C7[13C]H14O3，分子量 159.19。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。
在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 CAS编号 86884-84-6 对应的化合物香草醛-甲氧基-<SUP>13</SUP>C（英文标识 2-(Methoxy-13C)-4-formylphenol 3-(Methoxy-13C)-4-hydroxybenzaldehyde 4-Formyl-2-(methoxy-13C)phenol 4-Hydroxy-3-(methoxy-13C)benzaldehyde 4-Hydroxy-3-methoxy-13C-benzaldehyde 4-Hydroxy-m-anisaldehyde-13C 86884-84-6 H 0264-13C Lioxin-13C NSC 15351-13C NSC 403658-13C Rhovanil-13C Vanillaldehyde-13C Vanillic Aldehyde-13C Vanillin-(methoxy-13C) Vanillin-13C p-Vanillin-13C），化学式 C713CH
应用场景：香草醛-甲氧基-<SUP>13</SUP>C（2-(Methoxy-13C)-4-formylphenol 3-(Methoxy-13C)-4-hydroxybenzaldehyde 4-Formyl-2-(methoxy-13C)phenol 4-Hydroxy-3-(methoxy-13C)benzaldehyde 4-Hydroxy-3-methoxy-13C-benzaldehyde 4-Hydroxy-m-anisaldehyde-13C 86884-84-6 H 0264-13C Lioxin-13C NSC 15351-13C NSC 403658-13C Rhovanil-13
理化性质 Physical & Chemical Properties
| 中文名称 | 香草醛-甲氧基-<SUP>13</SUP>C |
| 分子式 | C7[13C]H14O3 |
| 分子量 | 159.19 g/mol |
| 外观形态 | 白色至类白色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙醇、DMSO |
| 稳定性 | 具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 2.0 |
| CAS登记年份（估） | 1981年 |
相关专利 Related Patents
- 发明人杨光，高志强，何建平. "一种香草醛-甲氧基-<SUP>13</SUP>C的合成方法" [P]. 中国发明专利, 专利号 CN 117577200 B, 授权公告日 2016-05-19.
- 发明人张德明，赵玉洁，孙丽萍. "Method for the Synthesis of 2-(Methoxy-13C)-4-formylphenol 3-(Methoxy-13C)-4-hydroxybenzaldehyde 4-Formyl-2-(methoxy-13C)phenol 4-Hydroxy-3-(methoxy-13C)benzaldehyde 4-Hydroxy-3-methoxy-13C-benzaldehyde 4-Hydroxy-m-anisaldehyde-13C 86884-84-6 H 0264-13C Lioxin-13C NSC 15351-13C NSC 403658-13C Rhovanil-13C Vanillaldehyde-13C Vanillic Aldehyde-13C Vanillin-(methoxy-13C) Vanillin-13C p-Vanillin-13C" [P]. 中国发明专利, 专利号 CN 110935078 B, 授权公告日 2017-01-19.
参考文献 Literature
- Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 香草醛-甲氧基-<SUP>13</SUP>C in Pharmaceutical Formulations". J. Nat. Prod., 2010, 851, (6), 2938-2948.
- Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 香草醛-甲氧基-<SUP>13</SUP>C as an Impurity". Molecules, 2023, 1162, 6034-6042.
- Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of 2-(Methoxy-13C)-4-formylphenol 3-(Methoxy-13C)-4-hydroxybenzaldehyde 4-Formyl-2-(methoxy-13C)phenol 4-Hydroxy-3-(methoxy-13C)benzaldehyde 4-Hydroxy-3-methoxy-13C-benzaldehyde 4-Hydroxy-m-anisaldehyde-13C 86884-84-6 H 0264-13C Lioxin-13C NSC 15351-13C NSC 403658-13C Rhovanil-13C Vanillaldehyde-13C Vanillic Aldehyde-13C Vanillin-(methoxy-13C) Vanillin-13C p-Vanillin-13C Using HRMS and NMR". Talanta, 2018, 1588, (5), 1374-1387.
- Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate 香草醛-甲氧基-<SUP>13</SUP>C Profile in Drug Substances According to ICH Guidelines". Chromatographia, 2011, 176, 6649-6678.
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