3-甲基吡唑-1-氨甲酰胺 CAS 873-50-7

873-50-7 1-Carbamoyl-3-methylpyrazole Formamide, N-(3-methyl-1-pyrazolyl)- 3-Methyl-1H-pyrazole-1-carboxamide 5-23-05-00010 (Beilstein Handbook Reference) BRN 0115536 1-Carbamoyl-3(5)-methylpyrazole EINECS 212-840-7 N-(3-Methyl-1-pyrazolyl)formamide NSC 51116 NSC 75630 1H-Pyrazole-1-carboxamide, 3-methyl-

纯度 97%+现货药物标准品
CAS 号873-50-7
分子式C5H11N3O
分子量129.16 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-甲基吡唑-1-氨甲酰胺 873-50-7 1-Carbamoyl-3-methylpyrazole Formamide, N-(3-methyl-1-pyrazolyl)- 3-Methyl-1H-pyrazole-1-carboxamide 5-23-05-00010 (Beilstein Handbook Reference) BRN 0115536 1-Carbamoyl-3(5)-methylpyrazole EINECS 212-840-7 N-(3-Methyl-1-pyrazolyl)formamide NSC 51116 NSC 75630 1H-Pyrazole-1-carboxamide, 3-methyl- CAS 873-50-7 结构式 Chemical Structure

产品介绍 Description

3-甲基吡唑-1-氨甲酰胺（英文名 873-50-7 1-Carbamoyl-3-methylpyrazole Formamide, N-(3-methyl-1-pyrazolyl)- 3-Methyl-1H-pyrazole-1-carboxamide 5-23-05-00010 (Beilstein Handbook Reference) BRN 0115536 1-Carbamoyl-3(5)-methylpyrazole EINECS 212-840-7 N-(3-Methyl-1-pyrazolyl)formamide NSC 51116 NSC 75630 1H-Pyrazole-1-carboxamide, 3-methyl-，CAS 873-50-7）属于药物标准品。分子式 C5H11N3O，分子量 129.16。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，3-甲基吡唑-1-氨甲酰胺的分子量为129.16 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C5H11N3O 的3-甲基吡唑-1-氨甲酰胺（873-50-7 1-Carbamoyl-3-methylpyrazole Formamide, N-(3-methyl-1-pyrazolyl)- 3-Methyl-1H-pyrazole-1-carboxamide 5-23-05-00010 (Beilstein Handbook Reference) BRN 0115536 1-Carbamoyl-3(5)-methylpyrazole EINECS 212-840-7 N-(3-Methyl-1-pyrazolyl)formamide NSC 51116 NSC 75630 1H-Pyrazole-1-carboxamide, 3-methyl-），其CAS登记号是 873-50-7，分子量为 129.16 g/mol。 依据分子式为 C5H11N3O 的3-甲基吡唑-1-氨甲酰胺结构特征，其分子内含酰胺类，含羟基，含醚键，这

应用场景：3-甲基吡唑-1-氨甲酰胺（873-50-7 1-Carbamoyl-3-methylpyrazole Formamide, N-(3-methyl-1-pyrazolyl)- 3-Methyl-1H-pyrazole-1-carboxamide 5-23-05-00010 (Beilstein Handbook Reference) BRN 0115536 1-Carbamoyl-3(5)-methylpyrazole EINECS 212-840-7 N-(3-Methyl-1-pyrazolyl)formamide NSC 51116 NSC 75630 1H-Pyrazole-1-ca

理化性质 Physical & Chemical Properties

中文名称3-甲基吡唑-1-氨甲酰胺
分子式C5H11N3O
分子量129.16 g/mol
外观形态白色至类白色液体。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1957年
含氮原子数3

相关专利 Related Patents

  1. 发明人孙丽萍，李文辉，陈志强. "一种3-甲基吡唑-1-氨甲酰胺的合成方法" [P]. 中国发明专利, 专利号 CN 115218269 B, 授权公告日 2018-09-01.
  2. 发明人黄志刚，罗永刚，钱学锋. "Method for the Synthesis of 873-50-7 1-Carbamoyl-3-methylpyrazole Formamide, N-(3-methyl-1-pyrazolyl)- 3-Methyl-1H-pyrazole-1-carboxamide 5-23-05-00010 (Beilstein Handbook Reference) BRN 0115536 1-Carbamoyl-3(5)-methylpyrazole EINECS 212-840-7 N-(3-Methyl-1-pyrazolyl)formamide NSC 51116 NSC 75630 1H-Pyrazole-1-carboxamide, 3-methyl-" [P]. 中国发明专利, 专利号 CN 115197973 A, 授权公告日 2017-01-12.
  3. 发明人孙丽萍，陈志强，冯建国. "A Process for Preparing High-Purity 873-50-7 1-Carbamoyl-3-methylpyrazole Formamide, N-(3-methyl-1-pyrazolyl)- 3-Methyl-1H-pyrazole-1-carboxamide 5-23-05-00010 (Beilstein Handbook Reference) BRN 0115536 1-Carbamoyl-3(5)-methylpyrazole EINECS 212-840-7 N-(3-Methyl-1-pyrazolyl)formamide NSC 51116 NSC 75630 1H-Pyrazole-1-carboxamide, 3-methyl-" [P]. 中国发明专利, 专利号 CN 116477623 B, 授权公告日 2023-01-12.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of 3-甲基吡唑-1-氨甲酰胺 in Pharmaceutical Formulations". J. Nat. Prod., 2012, 1475, (6), 5943-5964.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-甲基吡唑-1-氨甲酰胺 as an Impurity". Chemosphere, 2014, 551, (11), 2085-2097.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of 873-50-7 1-Carbamoyl-3-methylpyrazole Formamide, N-(3-methyl-1-pyrazolyl)- 3-Methyl-1H-pyrazole-1-carboxamide 5-23-05-00010 (Beilstein Handbook Reference) BRN 0115536 1-Carbamoyl-3(5)-methylpyrazole EINECS 212-840-7 N-(3-Methyl-1-pyrazolyl)formamide NSC 51116 NSC 75630 1H-Pyrazole-1-carboxamide, 3-methyl- Using HRMS and NMR". Anal. Chim. Acta, 2015, 2417, (1), 5851-5880.
  4. Wang L, Li J, Zhang H. "Forced Degradation Studies to Evaluate 3-甲基吡唑-1-氨甲酰胺 Profile in Drug Substances According to ICH Guidelines". Sci. Total Environ., 2017, 1215, (10), 3779-3787.

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