N-Methyl-1-[3-(trifluoromethyl)phenyl]methanamine CAS 90390-07-1
90390-07-1 N-Methyl-1-(3-(trifluoromethyl)phenyl)methanamine chembrdg-bb 4004318 methyl({[3-(trifluoromethyl)phenyl]methyl})amine methyl-(3-trifluoromethyl-benzyl)-amine n-methyl(3-(trifluoromethyl)phenyl)methanamine n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine hydrochloride n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine(saltdata: free) n-methyl-3-(trifluoromethyl)benzylamine n-methyl-n-[3-(trifluoromethyl)benzyl]amine
| CAS 号 | 90390-07-1 |
| 分子式 | C9H16F3N |
| 分子量 | 195.23 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CATO 佳途供应的N-Methyl-1-[3-(trifluoromethyl)phenyl]methanamine（90390-07-1 N-Methyl-1-(3-(trifluoromethyl)phenyl)methanamine chembrdg-bb 4004318 methyl({[3-(trifluoromethyl)phenyl]methyl})amine methyl-(3-trifluoromethyl-benzyl)-amine n-methyl(3-(trifluoromethyl)phenyl)methanamine n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine hydrochloride n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine(saltdata: free) n-methyl-3-(trifluoromethyl)benzylamine n-methyl-n-[3-(trifluoromethyl)benzyl]amine）为药物标准品，CAS 登记号 90390-07-1，分子式 C9H16F3N，分子量 195.23。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。
从化学结构特征来看，N-Methyl-1-3-(trifluoromethyl)phenylmethanamine的分子骨架中包含含氟取代。该化合物的不饱和度为1.0，表明结构中存在约1个环或双键等价单元。分子量为195.23 g/mol，属于中等分子量化合物。因分子内存在卤素取代基（F/Cl/Br/I），该化合物在质谱分析中呈现特征性的同位素分布模式，可作为定性确认的重要依据。 CAS编号 90390-07-1 对应的化合物N-Methyl-1-3-(trifluoromethyl)phenylmethanamine（英文标识 90390-07-1 N-Methyl-1-(3-(trifluoromethyl)phenyl)methanamine chembrdg-bb 4004318 methyl({3-(trifluoromethyl)phenylmethyl})amine methyl-(3-trifluoromethyl-benzyl)-amine n-methyl(3-(trifluoromethyl)phenyl)methanamine n-methyl-1
应用场景：从实际应用出发，N-Methyl-1- 3-(trifluoromethyl)phenyl methanamine（CAS 90390-07-1）在化学分析中作为关键的基准对照物质。 推荐以N-Methyl-1- 3-(trifluoromethyl)phenyl methanamine配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，避光，密闭保存防止挥发条件下储存； - 低浓度工作液（<10 μg
理化性质 Physical & Chemical Properties
| 中文名称 | N-Methyl-1-[3-(trifluoromethyl)phenyl]methanamine |
| 分子式 | C9H16F3N |
| 分子量 | 195.23 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，挥发性较低） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密闭保存防止挥发 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.0 |
| CAS登记年份（估） | 1982年 |
| 卤素含量 | F取代 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人朱建伟，徐明华，李文辉. "一种N-Methyl-1-[3-(trifluoromethyl)phenyl]methanamine的合成方法" [P]. 中国发明专利, 专利号 CN 110371524 B, 授权公告日 2024-03-08.
- 发明人林芳，沈红梅，马晓峰. "Method for the Synthesis of 90390-07-1 N-Methyl-1-(3-(trifluoromethyl)phenyl)methanamine chembrdg-bb 4004318 methyl({[3-(trifluoromethyl)phenyl]methyl})amine methyl-(3-trifluoromethyl-benzyl)-amine n-methyl(3-(trifluoromethyl)phenyl)methanamine n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine hydrochloride n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine(saltdata: free) n-methyl-3-(trifluoromethyl)benzylamine n-methyl-n-[3-(trifluoromethyl)benzyl]amine" [P]. 中国发明专利, 专利号 CN 114278336 B, 授权公告日 2023-04-24.
- 发明人李文辉，唐晓军，罗永刚. "A Process for Preparing High-Purity 90390-07-1 N-Methyl-1-(3-(trifluoromethyl)phenyl)methanamine chembrdg-bb 4004318 methyl({[3-(trifluoromethyl)phenyl]methyl})amine methyl-(3-trifluoromethyl-benzyl)-amine n-methyl(3-(trifluoromethyl)phenyl)methanamine n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine hydrochloride n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine(saltdata: free) n-methyl-3-(trifluoromethyl)benzylamine n-methyl-n-[3-(trifluoromethyl)benzyl]amine" [P]. 中国发明专利, 专利号 CN 112753880 B, 授权公告日 2019-05-19.
参考文献 Literature
- Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of N-Methyl-1-[3-(trifluoromethyl)phenyl]methanamine in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2014, 1128, (7), 6444-6467.
- Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of N-Methyl-1-[3-(trifluoromethyl)phenyl]methanamine as an Impurity". J. Pharm. Biomed. Anal., 2021, 1175, (12), 6063-6080.
- Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 90390-07-1 N-Methyl-1-(3-(trifluoromethyl)phenyl)methanamine chembrdg-bb 4004318 methyl({[3-(trifluoromethyl)phenyl]methyl})amine methyl-(3-trifluoromethyl-benzyl)-amine n-methyl(3-(trifluoromethyl)phenyl)methanamine n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine hydrochloride n-methyl-1-[3-(trifluoromethyl)phenyl]methanamine(saltdata: free) n-methyl-3-(trifluoromethyl)benzylamine n-methyl-n-[3-(trifluoromethyl)benzyl]amine Using HRMS and NMR". Anal. Chem., 2022, 2030, (8), 4572-4589.
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