CAS 93710-27-1

93710-27-1 Leuconolam Indolizino(8,1-ef)(1)benzazonine-6,13(5H,9H)-dione, 8a-ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxy-, stereoisomer 8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxyindolizino(8,1-ef)(1)benzazonine-6,13-(5H,9H)-dione Leuconolam sesquihydrate

纯度 97%+现货药物标准品
CAS 号93710-27-1
分子式C19H22N2O3
分子量326.39 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

93710-27-1 Leuconolam Indolizino(8,1-ef)(1)benzazonine-6,13(5H,9H)-dione, 8a-ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxy-, stereoisomer 8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxyindolizino(8,1-ef)(1)benzazonine-6,13-(5H,9H)-dione Leuconolam sesquihydrate CAS 93710-27-1 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品（93710-27-1 Leuconolam Indolizino(8,1-ef)(1)benzazonine-6,13(5H,9H)-dione, 8a-ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxy-, stereoisomer 8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxyindolizino(8,1-ef)(1)benzazonine-6,13-(5H,9H)-dione Leuconolam sesquihydrate，CAS 93710-27-1），分子式 C19H22N2O3，分子量 326.39。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

的产生途径与其化学式中甾体骨架，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C19H22N2O3 的（93710-27-1 Leuconolam Indolizino(8,1-ef)(1)benzazonine-6,13(5H,9H)-dione, 8a-ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxy-, stereoisomer 8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxyindolizino(8,1-ef)(1)benzazonine-6,13-(5H,9H)-dione Leuconolam sesquihydrate），其CAS登记号是 93710-27-1，分子量为 326.39 g/mol。 （分子式 C19H22N2O3）的化学结构中包含甾体骨架，酰胺类，含羟基，含醚键。在反相色谱体系中，其保留行为主要受含氮官能团的质子化状态影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。由于结构中存在共轭发色团

应用场景：针对化学分析用途，（93710-27-1 Leuconolam Indolizino(8,1-ef)(1)benzazonine-6,13(5H,9H)-dione, 8a-ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxy-, stereoisomer 8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxyindolizino(8,1-ef)(1)benzazonine-6,13-(5H,9H)-dione Leuconolam sesquihydrate）是具有明确定量溯源的认证级对照品。 推荐以配制标准系列工

理化性质 Physical & Chemical Properties

中文名称
分子式C19H22N2O3
分子量326.39 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1983年
含氮原子数2

相关专利 Related Patents

  1. 发明人孙丽萍，赵玉洁，何建平. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 114899787 B, 授权公告日 2020-08-21.
  2. Williams B T, Mueller T, Chen K W. "Method for the Synthesis of 93710-27-1 Leuconolam Indolizino(8,1-ef)(1)benzazonine-6,13(5H,9H)-dione, 8a-ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxy-, stereoisomer 8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxyindolizino(8,1-ef)(1)benzazonine-6,13-(5H,9H)-dione Leuconolam sesquihydrate" [P]. US Patent, US 9716856 B2, 2025-09-06.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Talanta, 2020, 906, (12), 6668-6691.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". J. Chromatogr. A, 2024, 347, 9253-9266.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of 93710-27-1 Leuconolam Indolizino(8,1-ef)(1)benzazonine-6,13(5H,9H)-dione, 8a-ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxy-, stereoisomer 8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxyindolizino(8,1-ef)(1)benzazonine-6,13-(5H,9H)-dione Leuconolam sesquihydrate Using HRMS and NMR". Environ. Sci. Technol., 2013, 353, (7), 8456-8469.

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