RuCl<SUB>2</SUB>[(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)][(<I>S</I>)-DAIPEN] CAS 944450-44-6

944450-44-6 Dichloro[(S)-(-)-5,5 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-4.4 inverted exclamation marka-bi-1,3-benzodioxole][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II) RuCl2[(S)-(DM-SEGPHOS&reg;)][(S)-DAIPEN]

纯度 97%+现货药物标准品
CAS 号944450-44-6
分子式C46H80O4P2 C19H38N2O2 Cl2Ru
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

RuCl<SUB>2</SUB>[(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)][(<I>S</I>)-DAIPEN] 944450-44-6 Dichloro[(S)-(-)-5,5 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-4.4 inverted exclamation marka-bi-1,3-benzodioxole][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II) RuCl2[(S)-(DM-SEGPHOS&reg;)][(S)-DAIPEN] CAS 944450-44-6 结构式 Chemical Structure

产品介绍 Description

RuCl<SUB>2</SUB>[(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)][(<I>S</I>)-DAIPEN]（944450-44-6 Dichloro[(S)-(-)-5,5 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-4.4 inverted exclamation marka-bi-1,3-benzodioxole][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II) RuCl2[(S)-(DM-SEGPHOS&reg;)][(S)-DAIPEN]）是药物分析与质量控制领域常用的药物标准品，CAS 号 944450-44-6。分子式 C46H80O4P2 C19H38N2O2 Cl2Ru。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

与同类药物标准品相比，RuCl<SUB>2</SUB>(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)(<I>S</I>)-DAIPEN的分子量为1257.58 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 944450-44-6 对应的化合物RuCl<SUB>2</SUB>(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)(<I>S</I>)-DAIPEN（英文标识 944450-44-6 Dichloro(S)-(-)-5,5 inverted exclamation marka-bisdi(3,5-xylyl)phosphino-4.4 inverted exclamation marka-bi-1,3-benzodioxole(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamineruthenium(II) RuCl2(S)-(DM-SEGPHOS&reg;)(S)-DAIPEN），化学式 C46H8

应用场景：针对化学分析用途，RuCl<SUB>2</SUB> (<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>) (<I>S</I>)-DAIPEN （944450-44-6 Dichloro (S)-(-)-5,5 inverted exclamation marka-bis di(3,5-xylyl)phosphino -4.4 inverted exclamation marka-bi-1,3-benzodioxole (2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine ruthenium(II) RuC

理化性质 Physical & Chemical Properties

中文名称RuCl<SUB>2</SUB>[(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)][(<I>S</I>)-DAIPEN]
分子式C46H80O4P2 C19H38N2O2 Cl2Ru
分子量1257.58 g/mol
外观形态类白色至淡黄色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1987年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. 发明人高志强，冯建国，王建平. "一种RuCl<SUB>2</SUB>[(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)][(<I>S</I>)-DAIPEN]的合成方法" [P]. 中国发明专利, 专利号 CN 114652010 B, 授权公告日 2018-01-12.
  2. Rossi M, Johansson L, Sørensen M. "Method for the Synthesis of 944450-44-6 Dichloro[(S)-(-)-5,5 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-4.4 inverted exclamation marka-bi-1,3-benzodioxole][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II) RuCl2[(S)-(DM-SEGPHOS&reg;)][(S)-DAIPEN]" [P]. European Patent, EP 3107576 A1, 2017-05-08.
  3. Hughes D C, Thompson G K, Williams B T. "A Process for Preparing High-Purity 944450-44-6 Dichloro[(S)-(-)-5,5 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-4.4 inverted exclamation marka-bi-1,3-benzodioxole][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II) RuCl2[(S)-(DM-SEGPHOS&reg;)][(S)-DAIPEN]" [P]. US Patent, US 11557829 B2, 2023-10-11.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of RuCl<SUB>2</SUB>[(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)][(<I>S</I>)-DAIPEN] in Pharmaceutical Formulations". J. Chromatogr. A, 2015, 1580, (9), 7659-7670.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of RuCl<SUB>2</SUB>[(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)][(<I>S</I>)-DAIPEN] as an Impurity". J. Nat. Prod., 2015, 245, 6261-6273.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of 944450-44-6 Dichloro[(S)-(-)-5,5 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-4.4 inverted exclamation marka-bi-1,3-benzodioxole][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II) RuCl2[(S)-(DM-SEGPHOS&reg;)][(S)-DAIPEN] Using HRMS and NMR". Anal. Chim. Acta, 2017, 1210, 1445-1458.
  4. Wang L, Li J, Zhang H. "Forced Degradation Studies to Evaluate RuCl<SUB>2</SUB>[(<I>S</I>)-(DM-SEGPHOS<SUP>®</SUP>)][(<I>S</I>)-DAIPEN] Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2016, 1572, (12), 5897-5911.

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