<I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸 CAS 947533-31-5

1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4-boronic acid, n-boc protected 947533-31-5 n-boc-1h-pyrazole-4-boronic acid

纯度 97%+现货药物标准品
CAS 号947533-31-5
分子式C8H17BN2O4
分子量216.04 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

<I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸 1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4-boronic acid, n-boc protected 947533-31-5 n-boc-1h-pyrazole-4-boronic acid CAS 947533-31-5 结构式 Chemical Structure

产品介绍 Description

<I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸（英文名 1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4-boronic acid, n-boc protected 947533-31-5 n-boc-1h-pyrazole-4-boronic acid，CAS 947533-31-5）属于药物标准品。分子式 C8H17BN2O4，分子量 216.04。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

受分子结构中氨基酸衍生物，酰胺类，含羟基，含醚键的影响，<I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸表现为白色至类白色结晶性粉末。（具有氨/胺类微弱气味）。其固体形态的物理化学属性——包括216.04 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率，适合LC-MS/MS分析。 CAS编号 947533-31-5 对应的化合物<I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸（英文标识 1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4

应用场景：<I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸（1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4-boronic acid, n-boc pro

理化性质 Physical & Chemical Properties

中文名称<I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸
分子式C8H17BN2O4
分子量216.04 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）1987年
含氮原子数2

相关专利 Related Patents

  1. 发明人杨光，刘建华，赵玉洁. "一种<I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸的合成方法" [P]. 中国发明专利, 专利号 CN 116248970 B, 授权公告日 2021-02-28.
  2. 发明人周伟，陈志强，赵玉洁. "Method for the Synthesis of 1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4-boronic acid, n-boc protected 947533-31-5 n-boc-1h-pyrazole-4-boronic acid" [P]. 中国发明专利, 专利号 CN 110970313 B, 授权公告日 2025-04-19.
  3. Hughes D C, Anderson J P, Lee S K. "A Process for Preparing High-Purity 1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4-boronic acid, n-boc protected 947533-31-5 n-boc-1h-pyrazole-4-boronic acid" [P]. US Patent, US 11766907 B2, 2020-10-02.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of <I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸 in Pharmaceutical Formulations". Molecules, 2020, 1000, 7909-7921.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of <I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸 as an Impurity". Anal. Chim. Acta, 2011, 2015, 1546-1550.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4-boronic acid, n-boc protected 947533-31-5 n-boc-1h-pyrazole-4-boronic acid Using HRMS and NMR". Anal. Chem., 2012, 1384, (12), 2667-2693.
  4. Mueller T, Schmidt R K. "Forced Degradation Studies to Evaluate <I>N</I>-Boc-1<I>H</I>-吡唑-4-硼酸 Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2013, 1838, 7605-7626.

Related tert Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...