发明人黄志刚,王建平,马晓峰. "Method for the Synthesis of 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole magnesium salt (2:1)
95500-19-9
Diethyldimethylammonium hydroxide
diethyldimethylammonium hydroxide ,0% [20% in h2o]
diethyldimethylammonium hydroxide [20% in h2o]
diethyldimethylammonium hydroxide sol., ~20% in water
diethyldimethylammoniumhydroxidesolution
dimethyldiethylammonium hydroxide
dimethyldiethylammonium hydroxide, 20% aq
ethanaminium,n-ethyl-n,n-dimethyl-,hydroxide" [P]. 中国发明专利, 专利号 CN 114616448 B, 授权公告日 2015-09-01.
Schröder R, Brown S R, O'Brien P Q. "A Process for Preparing High-Purity 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole magnesium salt (2:1)
95500-19-9
Diethyldimethylammonium hydroxide
diethyldimethylammonium hydroxide ,0% [20% in h2o]
diethyldimethylammonium hydroxide [20% in h2o]
diethyldimethylammonium hydroxide sol., ~20% in water
diethyldimethylammoniumhydroxidesolution
dimethyldiethylammonium hydroxide
dimethyldiethylammonium hydroxide, 20% aq
ethanaminium,n-ethyl-n,n-dimethyl-,hydroxide" [P]. US Patent, US 11165664 B2, 2024-11-05.
参考文献 Literature
Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of 二乙基二甲基氢氧化铵 溶液 in Pharmaceutical Formulations". Chromatographia, 2023, 903, 7476-7497.
Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of 二乙基二甲基氢氧化铵 溶液 as an Impurity". J. Sep. Sci., 2023, 461, 1011-1035.
Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole magnesium salt (2:1)
95500-19-9
Diethyldimethylammonium hydroxide
diethyldimethylammonium hydroxide ,0% [20% in h2o]
diethyldimethylammonium hydroxide [20% in h2o]
diethyldimethylammonium hydroxide sol., ~20% in water
diethyldimethylammoniumhydroxidesolution
dimethyldiethylammonium hydroxide
dimethyldiethylammonium hydroxide, 20% aq
ethanaminium,n-ethyl-n,n-dimethyl-,hydroxide Using HRMS and NMR". Anal. Chim. Acta, 2020, 1163, (11), 8300-8329.
Kowalski T, Nowak Z. "Forced Degradation Studies to Evaluate 二乙基二甲基氢氧化铵 溶液 Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2013, 617, (8), 2148-2165.