3-（丙烯酰胺基）苯硼酸 CAS 99349-68-5
(m-Acrylamidophenyl)boronic acid 3 - Acrylamidophenylboronic acid 3-(acrylamido)phenylboronic acid 98% 3-(acrylamido)phenylboronic acid, 3-[(prop-2-enoyl)amino]benzeneboronic acid 3-(acryloylamino)benzeneboronic acid 3-(acryloylamino)phenylboronic acid 3-(propenamido)phenylboronic acid 99349-68-5 boronic acid acrylamide boronic acid, [3-[(1-oxo-2-propenyl)amino]phenyl]- boronic acid, b-[3-[(1-oxo-2-propen-1-yl)amino]phenyl]- n-acryloyl-3-aminophenylboronic acid
| CAS 号 | 99349-68-5 |
| 分子式 | C9H16BNO3 |
| 分子量 | 197.04 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
3-（丙烯酰胺基）苯硼酸（(m-Acrylamidophenyl)boronic acid 3 - Acrylamidophenylboronic acid 3-(acrylamido)phenylboronic acid 98% 3-(acrylamido)phenylboronic acid, 3-[(prop-2-enoyl)amino]benzeneboronic acid 3-(acryloylamino)benzeneboronic acid 3-(acryloylamino)phenylboronic acid 3-(propenamido)phenylboronic acid 99349-68-5 boronic acid acrylamide boronic acid, [3-[(1-oxo-2-propenyl)amino]phenyl]- boronic acid, b-[3-[(1-oxo-2-propen-1-yl)amino]phenyl]- n-acryloyl-3-aminophenylboronic acid，CAS 号 99349-68-5）是 CATO 佳途自主生产的药物标准品，分子式 C9H16BNO3，分子量 197.04。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。
本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 3-（丙烯酰胺基）苯硼酸（(m-Acrylamidophenyl)boronic acid 3 - Acrylamidophenylboronic acid 3-(acrylamido)phenylboronic acid 98% 3-(acrylamido)phenylboronic acid, 3-(prop-2-enoyl)aminobenzeneboronic acid 3-(acryloylamino)benzeneboronic acid 3-(acryloylamino)phenylboronic acid 3-(propenamido)phenylboronic acid 99349-68-5 boronic acid acrylamide boronic acid, 3-(1-oxo-2-propenyl)aminophenyl- boronic acid, b-3-(1-oxo-2-prope
应用场景：3-（丙烯酰胺基）苯硼酸（(m-Acrylamidophenyl)boronic acid 3 - Acrylamidophenylboronic acid 3-(acrylamido)phenylboronic acid 98% 3-(acrylamido)phenylboronic acid, 3- (prop-2-enoyl)amino benzeneboronic acid 3-(acryloylamino)benzeneboronic acid 3-(acryloylamino)phenylboronic acid 3-(propenamido)phenylboronic acid
理化性质 Physical & Chemical Properties
| 中文名称 | 3-（丙烯酰胺基）苯硼酸 |
| 分子式 | C9H16BNO3 |
| 分子量 | 197.04 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（具有氨/胺类微弱气味） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙醇、DMSO |
| 稳定性 | 对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 2.5 |
| CAS登记年份（估） | 1985年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人唐晓军，朱建伟，陈志强. "一种3-（丙烯酰胺基）苯硼酸的合成方法" [P]. 中国发明专利, 专利号 CN 109609856 A, 授权公告日 2022-01-21.
- Hughes D C, Johnson M A, Patel M V. "Method for the Synthesis of (m-Acrylamidophenyl)boronic acid 3 - Acrylamidophenylboronic acid 3-(acrylamido)phenylboronic acid 98% 3-(acrylamido)phenylboronic acid, 3-[(prop-2-enoyl)amino]benzeneboronic acid 3-(acryloylamino)benzeneboronic acid 3-(acryloylamino)phenylboronic acid 3-(propenamido)phenylboronic acid 99349-68-5 boronic acid acrylamide boronic acid, [3-[(1-oxo-2-propenyl)amino]phenyl]- boronic acid, b-[3-[(1-oxo-2-propen-1-yl)amino]phenyl]- n-acryloyl-3-aminophenylboronic acid" [P]. US Patent, US 9532451 B2, 2017-09-25.
参考文献 Literature
- Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of 3-（丙烯酰胺基）苯硼酸 in Pharmaceutical Formulations". Chromatographia, 2025, 1010, (1), 9802-9812.
- Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-（丙烯酰胺基）苯硼酸 as an Impurity". Environ. Sci. Technol., 2024, 657, (12), 8381-8393.
- Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of (m-Acrylamidophenyl)boronic acid 3 - Acrylamidophenylboronic acid 3-(acrylamido)phenylboronic acid 98% 3-(acrylamido)phenylboronic acid, 3-[(prop-2-enoyl)amino]benzeneboronic acid 3-(acryloylamino)benzeneboronic acid 3-(acryloylamino)phenylboronic acid 3-(propenamido)phenylboronic acid 99349-68-5 boronic acid acrylamide boronic acid, [3-[(1-oxo-2-propenyl)amino]phenyl]- boronic acid, b-[3-[(1-oxo-2-propen-1-yl)amino]phenyl]- n-acryloyl-3-aminophenylboronic acid Using HRMS and NMR". Anal. Chem., 2022, 2299, 6492-6517.
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