CAS 104884-43-7

104884-43-7 T 506 5'-Uridylic acid, 2'-deoxy-5-fluoro-, mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- T-506 5-Fluoro-2'-deoxy-3'-O-oleoyluridine-5'-(2-trimethylammoninoethyl)phosphate Mono(2-(trimethylammonio)ethyl) 2'-deoxy-5-fluoro-5'-uridylate hydroxide, inner salt, 3'-(9-octadecenoate), (Z)-

纯度 97%+现货药物标准品
CAS 号104884-43-7
分子式C32H55FN3O9P
分子量675.77 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

104884-43-7 T 506 5'-Uridylic acid, 2'-deoxy-5-fluoro-, mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- T-506 5-Fluoro-2'-deoxy-3'-O-oleoyluridine-5'-(2-trimethylammoninoethyl)phosphate Mono(2-(trimethylammonio)ethyl) 2'-deoxy-5-fluoro-5'-uridylate hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- CAS 104884-43-7 结构式 Chemical Structure

产品介绍 Description

CAS 104884-43-7 对应的（104884-43-7 T 506 5'-Uridylic acid, 2'-deoxy-5-fluoro-, mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- T-506 5-Fluoro-2'-deoxy-3'-O-oleoyluridine-5'-(2-trimethylammoninoethyl)phosphate Mono(2-(trimethylammonio)ethyl) 2'-deoxy-5-fluoro-5'-uridylate hydroxide, inner salt, 3'-(9-octadecenoate), (Z)-）为 CATO 佳途药物标准品产品线成员。分子式 C32H55FN3O9P，分子量 675.77。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

作为认证标准物质（CRM），满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 化学式为 C32H55FN3O9P 的（104884-43-7 T 506 5'-Uridylic acid, 2'-deoxy-5-fluoro-, mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- T-506 5-Fluoro-2'-deoxy-3'-O-oleoyluridine-5'-(2-trimethylammoninoethyl)phosphate Mono(2-(trimethylammonio)ethyl) 2'-deoxy-5-fluoro-5'-uridylate hydroxide, inner salt, 3'-(9-octadecenoate), (Z)-），其CAS登记号是 104884-43-7，分子量为 675

应用场景：针对化学分析用途，（104884-43-7 T 506 5'-Uridylic acid, 2'-deoxy-5-fluoro-, mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- T-506 5-Fluoro-2'-deoxy-3'-O-oleoyluridine-5'-(2-trimethylammoninoethyl)phosphate Mono(2-(trimethylammonio)ethyl) 2'-deoxy-5-fluoro-5'-uridylate

理化性质 Physical & Chemical Properties

中文名称
分子式C32H55FN3O9P
分子量675.77 g/mol
外观形态类白色至淡黄色无定形粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1986年
卤素含量F取代
含氮原子数3

相关专利 Related Patents

  1. Schröder R, Chen K W, Fischer A B. "一种的合成方法" [P]. US Patent, US 9191591 B2, 2016-09-10.
  2. 发明人唐晓军，王建平，林芳. "Method for the Synthesis of 104884-43-7 T 506 5'-Uridylic acid, 2'-deoxy-5-fluoro-, mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- T-506 5-Fluoro-2'-deoxy-3'-O-oleoyluridine-5'-(2-trimethylammoninoethyl)phosphate Mono(2-(trimethylammonio)ethyl) 2'-deoxy-5-fluoro-5'-uridylate hydroxide, inner salt, 3'-(9-octadecenoate), (Z)-" [P]. 中国发明专利, 专利号 CN 111979244 B, 授权公告日 2022-10-18.
  3. 发明人胡光，张德明，马晓峰. "A Process for Preparing High-Purity 104884-43-7 T 506 5'-Uridylic acid, 2'-deoxy-5-fluoro-, mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- T-506 5-Fluoro-2'-deoxy-3'-O-oleoyluridine-5'-(2-trimethylammoninoethyl)phosphate Mono(2-(trimethylammonio)ethyl) 2'-deoxy-5-fluoro-5'-uridylate hydroxide, inner salt, 3'-(9-octadecenoate), (Z)-" [P]. 中国发明专利, 专利号 CN 108492082 B, 授权公告日 2024-01-27.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Anal. Methods, 2012, 324, 7217-7226.
  2. Yang F, Sun W, Liu J. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Talanta, 2018, 2055, 5563-5575.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of 104884-43-7 T 506 5'-Uridylic acid, 2'-deoxy-5-fluoro-, mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- T-506 5-Fluoro-2'-deoxy-3'-O-oleoyluridine-5'-(2-trimethylammoninoethyl)phosphate Mono(2-(trimethylammonio)ethyl) 2'-deoxy-5-fluoro-5'-uridylate hydroxide, inner salt, 3'-(9-octadecenoate), (Z)- Using HRMS and NMR". Sci. Total Environ., 2010, 635, (11), 1676-1679.

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