2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride CAS 1049790-17-1

2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride

纯度 97%+现货药物标准品
CAS 号1049790-17-1
分子式C16H11F6N3O2 HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride 2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride CAS 1049790-17-1 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride（2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride）为药物标准品，CAS 登记号 1049790-17-1，分子式 C16H11F6N3O2 HCl。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括2-({2-oxo-2-(2,3,4-trifluorophenyl)aminoethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride在内的目标物的控制。 化学式为 C16H11F6N3O2 HCl 的2-({2-oxo-2-(2,3,4-trifluorophenyl)aminoethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride（2-({2-oxo-2-(2,3,4-trifluorophenyl)aminoethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride），其CAS登记号是 1049790-17-1，分子量为 427.73 g/mol。 2-({2-oxo-2-(2,3,4-trifluorophenyl)aminoethyl}amino)-N-(2,3,4-trifluorophenyl)a

应用场景：在化学分析实验室中，2-({2-oxo-2- (2,3,4-trifluorophenyl)amino ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride（CAS 1049790-17-1）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以2-({2-oxo-2- (2,3,4-trifluorophenyl)amino ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用

理化性质 Physical & Chemical Properties

中文名称2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride
分子式C16H11F6N3O2 HCl
分子量427.73 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1988年
卤素含量F/Cl取代
含氮原子数3

相关专利 Related Patents

  1. 发明人刘建华，罗永刚，孙丽萍. "一种2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 112225437 B, 授权公告日 2021-05-06.
  2. Kowalski A, Sørensen M, Nowak P. "Method for the Synthesis of 2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride" [P]. European Patent, EP 3174135 A1, 2017-09-01.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride in Pharmaceutical Formulations". J. Sep. Sci., 2018, 834, (6), 6201-6231.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride as an Impurity". J. Pharm. Biomed. Anal., 2013, 668, (2), 7025-7052.
  3. Zhang Y, Li Q, Chen T. "Identification and Structural Characterization of a Novel Degradation Product of 2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2011, 1541, 3130-3138.
  4. Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate 2-({2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl}amino)-N-(2,3,4-trifluorophenyl)acetamide hydrochloride Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2016, 2149, 1677-1681.

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