1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid CAS 1098365-93-5

1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid

纯度 97%+现货药物标准品
CAS 号1098365-93-5
分子式C13H16N2O4
分子量264.28 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid 1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid CAS 1098365-93-5 结构式 Chemical Structure

产品介绍 Description

1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid（1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid，CAS 号 1098365-93-5）是 CATO 佳途自主生产的药物标准品，分子式 C13H16N2O4，分子量 264.28。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

化学式为 C13H16N2O4 的1-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonylpiperidine-4-carboxylic acid（1-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonylpiperidine-4-carboxylic acid），其CAS登记号是 1098365-93-5，分子量为 264.28 g/mol。 从化学结构特征来看，1-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonylpiperidine-4-carboxylic acid的分子骨架中包含含氮杂环结构，酰胺类，含羟基，含醚键。该化合物的不饱和度为7.0，表明结构中存在约7个环或双键等价单元。分子量为264.28 g/mol，属于中等分子量化合物。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率，适合LC-MS/MS分析。 推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯

应用场景：1- (1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl piperidine-4-carboxylic acid（1- (1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl piperidine-4-carboxylic acid，CAS 1098365-93-5）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以1- (1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl piperidine-4-carboxylic acid配制标准系列工作溶液，用

理化性质 Physical & Chemical Properties

中文名称1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid
分子式C13H16N2O4
分子量264.28 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1989年
含氮原子数2

相关专利 Related Patents

  1. 发明人林芳，周伟，韩伟. "一种1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid的合成方法" [P]. 中国发明专利, 专利号 CN 113447695 A, 授权公告日 2021-04-14.
  2. 发明人刘建华，郑宇鹏，何建平. "Method for the Synthesis of 1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid" [P]. 中国发明专利, 专利号 CN 117816800 B, 授权公告日 2025-04-12.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of 1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2021, 1384, 283-290.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid as an Impurity". Environ. Sci. Technol., 2019, 1285, 272-276.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 1-[(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)carbonyl]piperidine-4-carboxylic acid Using HRMS and NMR". Chemosphere, 2016, 1431, (8), 9259-9262.

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