3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid CAS 1172048-86-0

3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid

纯度 97%+现货药物标准品
CAS 号1172048-86-0
分子式C14H16N6O2
分子量300.32 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid 3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid CAS 1172048-86-0 结构式 Chemical Structure

产品介绍 Description

3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid（3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid）是药物分析与质量控制领域常用的药物标准品，CAS 号 1172048-86-0。分子式 C14H16N6O2，分子量 300.32。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

3-7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)1,2,4triazolo1,5-apyrimidin-2-ylpropanoic acid的产生途径与其化学式中含氮杂环结构，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C14H16N6O2 的3-7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)1,2,4triazolo1,5-apyrimidin-2-ylpropanoic acid（3-7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)1,2,4triazolo1,5-apyrimidin-2-ylpropanoic acid），其CAS登记号是 1172048-86-0，分子量为 300.32 g/mol。 3-7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)1,2,4triazolo1,5-apyrimidin-2-ylpropanoic acid（C14H16N6O2）

应用场景：3- 7-(1-ethyl-3-methyl-1H-pyrazol-4-yl) 1,2,4 triazolo 1,5-a pyrimidin-2-yl propanoic acid（3- 7-(1-ethyl-3-methyl-1H-pyrazol-4-yl) 1,2,4 triazolo 1,5-a pyrimidin-2-yl propanoic acid）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以3- 7-(1-ethyl-3-methyl-1H-pyrazol-4-yl) 1,2,4 triazolo 1,5-a pyrimidin-2-yl propanoic a

理化性质 Physical & Chemical Properties

中文名称3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid
分子式C14H16N6O2
分子量300.32 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1989年
含氮原子数6

相关专利 Related Patents

  1. 发明人陈志强，沈红梅，郑宇鹏. "一种3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid的合成方法" [P]. 中国发明专利, 专利号 CN 113878256 B, 授权公告日 2018-09-21.
  2. Roberts E F, Patel M V, Kumar R. "Method for the Synthesis of 3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid" [P]. US Patent, US 11598795 B2, 2021-08-05.
  3. 发明人马晓峰，刘建华，何建平. "A Process for Preparing High-Purity 3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid" [P]. 中国发明专利, 专利号 CN 115848406 A, 授权公告日 2024-05-10.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of 3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid in Pharmaceutical Formulations". J. Chromatogr. A, 2025, 2428, (5), 6189-6198.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid as an Impurity". J. Nat. Prod., 2010, 1789, 532-545.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 3-[7-(1-ethyl-3-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid Using HRMS and NMR". J. Agric. Food Chem., 2012, 1018, (10), 7901-7930.

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