2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid CAS 1221723-96-1

2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid

纯度 97%+现货药物标准品
CAS 号1221723-96-1
分子式C12H10N2O4S2
分子量310.35 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid 2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid CAS 1221723-96-1 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid（2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid）为药物标准品，CAS 登记号 1221723-96-1，分子式 C12H10N2O4S2，分子量 310.35。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-1,3thiazolo2,3-c1,2,4thiadiazine-7-carboxylic acid在内的目标物的控制。 CAS编号 1221723-96-1 对应的化合物2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-1,3thiazolo2,3-c1,2,4thiadiazine-7-carboxylic acid（英文标识 2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-1,3thiazolo2,3-c1,2,4thiadiazine-7-carboxylic acid），化学式 C12H10N2O4S2，相对分子质量 310.35。 2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-1,3thiazolo2,3-c1,2,4thiadiazine-7-car

应用场景：从实际应用出发，2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000- 1,3 thiazolo 2,3-c 1,2,4 thiadiazine-7-carboxylic acid（CAS 1221723-96-1）在化学分析中作为关键的基准对照物质。 推荐以2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000- 1,3 thiazolo 2,3-c 1,2,4 thiadiazine-7-carboxylic acid配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备

理化性质 Physical & Chemical Properties

中文名称2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid
分子式C12H10N2O4S2
分子量310.35 g/mol
外观形态淡黄色至黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1990年
含氮原子数2
含硫原子数2

相关专利 Related Patents

  1. Chen K W, Park J H, Hughes D C. "一种2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid的合成方法" [P]. US Patent, US 9901428 B2, 2015-08-17.
  2. 发明人唐晓军，钱学锋，杨光. "Method for the Synthesis of 2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid" [P]. 中国发明专利, 专利号 CN 117165698 A, 授权公告日 2021-01-16.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid in Pharmaceutical Formulations". Biomed. Chromatogr., 2010, 1059, (11), 9680-9694.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid as an Impurity". Chromatographia, 2011, 2284, (4), 3777-3785.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid Using HRMS and NMR". Anal. Methods, 2011, 1048, 5760-5781.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate 2,2-dioxo-6-phenyl-3H,4H-2$l^{6},8,1,5000000-[1,3]thiazolo[2,3-c][1,2,4]thiadiazine-7-carboxylic acid Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2012, 1581, 7686-7710.

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