[1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride CAS 1286273-94-6

[1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride

纯度 97%+现货药物标准品
CAS 号1286273-94-6
分子式C12H24N2 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

[1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride [1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride CAS 1286273-94-6 结构式 Chemical Structure

产品介绍 Description

[1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride（[1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride）是药物分析与质量控制领域常用的药物标准品，CAS 号 1286273-94-6。分子式 C12H24N2 2*HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括1-(Cyclopentylmethyl)piperidin-4-ylmethanamine dihydrochloride在内的目标物的控制。 CAS编号 1286273-94-6 对应的化合物1-(Cyclopentylmethyl)piperidin-4-ylmethanamine dihydrochloride（英文标识 1-(Cyclopentylmethyl)piperidin-4-ylmethanamine dihydrochloride），化学式 C12H24N2 2HCl，相对分子质量 232.80。 受分子结构中含氯取代的影响，1-(Cyclopentylmethyl)piperidin-4-ylmethanamine dihydrochloride表现为白色至类白色低熔点固体。（具有轻微卤代物特征气味）。其固体形态的物理化学属性——包括232.80 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。卤素原子的引入增加了化合物的电负性，在ECD（电子捕获检测器）

应用场景： 1-(Cyclopentylmethyl)piperidin-4-yl methanamine dihydrochloride（ 1-(Cyclopentylmethyl)piperidin-4-yl methanamine dihydrochloride，CAS 1286273-94-6）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以 1-(Cyclopentylmethyl)piperidin-4-yl methanamine dihydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。

理化性质 Physical & Chemical Properties

中文名称[1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride
分子式C12H24N2 2*HCl
分子量232.80 g/mol
外观形态白色至类白色低熔点固体。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1990年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. 发明人胡光，徐明华，钱学锋. "一种[1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 113496512 A, 授权公告日 2024-08-17.
  2. Williams B T, O'Brien P Q, Patel M V. "Method for the Synthesis of [1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride" [P]. US Patent, US 11189776 B2, 2023-10-05.
  3. Park J H, Lee S K, Chen K W. "A Process for Preparing High-Purity [1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride" [P]. US Patent, US 11211000 B2, 2023-07-04.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of [1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride in Pharmaceutical Formulations". J. Chromatogr. A, 2017, 701, 3485-3511.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of [1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride as an Impurity". Phytochemistry, 2014, 2442, (5), 7972-7996.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of [1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride Using HRMS and NMR". Food Chem., 2016, 204, (4), 926-942.
  4. Kowalski T, Nowak Z. "Forced Degradation Studies to Evaluate [1-(Cyclopentylmethyl)piperidin-4-yl]methanamine dihydrochloride Profile in Drug Substances According to ICH Guidelines". Talanta, 2016, 2250, (3), 3379-3409.

Related Cyclopentylmethyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...