5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride CAS 1306603-95-1

5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride

纯度 97%+现货药物标准品
CAS 号1306603-95-1
分子式C14H16N4O2 HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride CAS 1306603-95-1 结构式 Chemical Structure

产品介绍 Description

5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride（英文名 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride，CAS 1306603-95-1）属于药物标准品。分子式 C14H16N4O2 HCl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride在内的目标物的控制。 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride（5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride），CAS注册编号 1306603-95-1，化学分子式为 C14H16N4O2 HCl，分子量 308.77 g/mol。 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-

应用场景：5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride（5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride，CAS 1306603-95-1）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以5-methyl-1-(2-methyl-1,2,3,4-tetrahydroi

理化性质 Physical & Chemical Properties

中文名称5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride
分子式C14H16N4O2 HCl
分子量308.77 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1990年
卤素含量Cl取代
含氮原子数4

相关专利 Related Patents

  1. 发明人徐明华，朱建伟，马晓峰. "一种5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 115486752 B, 授权公告日 2021-09-25.
  2. 发明人钱学锋，罗永刚，刘建华. "Method for the Synthesis of 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride" [P]. 中国发明专利, 专利号 CN 115678871 B, 授权公告日 2024-05-24.
  3. Hughes D C, Fischer A B, Roberts E F. "A Process for Preparing High-Purity 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride" [P]. US Patent, US 9966304 B2, 2015-08-22.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride in Pharmaceutical Formulations". Sci. Total Environ., 2013, 1554, (5), 1117-1134.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride as an Impurity". J. Chromatogr. A, 2019, 1976, (6), 2919-2936.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride Using HRMS and NMR". J. Nat. Prod., 2023, 1321, 6603-6626.
  4. Smith J A, Johnson M B. "Forced Degradation Studies to Evaluate 5-methyl-1-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2014, 1847, (7), 1941-1962.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...