CAS 131179-95-8

J81E81G364 131179-95-8 Efaproxiral [USAN:INN] Efaproxiral Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl- 2-(4-(((3,5-Dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid 2-Dacmpp RSR 13 Efaproxyn 2-(4-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanic acid UNII-J81E81G364 RSR13

纯度 97%+现货药物标准品
CAS 号131179-95-8
分子式C20H23NO4
分子量341.40 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

J81E81G364 131179-95-8 Efaproxiral [USAN:INN] Efaproxiral Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl- 2-(4-(((3,5-Dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid 2-Dacmpp RSR 13 Efaproxyn 2-(4-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanic acid UNII-J81E81G364 RSR13 CAS 131179-95-8 结构式 Chemical Structure

产品介绍 Description

（英文名 J81E81G364 131179-95-8 Efaproxiral [USAN:INN] Efaproxiral Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl- 2-(4-(((3,5-Dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid 2-Dacmpp RSR 13 Efaproxyn 2-(4-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanic acid UNII-J81E81G364 RSR13，CAS 131179-95-8）属于药物标准品。分子式 C20H23NO4，分子量 341.40。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 CAS编号 131179-95-8 对应的化合物（英文标识 J81E81G364 131179-95-8 Efaproxiral USAN:INN Efaproxiral Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl- 2-(4-(((3,5-Dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid 2-Dacmpp RSR 13 Efaproxyn 2-(4-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanic acid UNII-J81E81G364 RSR13），化学式 C20H23NO4，相对分子质量 341.40。 （C20H23NO4）含有黄酮骨架，酰胺

应用场景：（J81E81G364 131179-95-8 Efaproxiral USAN:INN Efaproxiral Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl- 2-(4-(((3,5-Dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid 2-Dacmpp RSR 13 Efaproxyn 2-(4-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-me

理化性质 Physical & Chemical Properties

中文名称
分子式C20H23NO4
分子量341.40 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1994年
含氮原子数1

相关专利 Related Patents

  1. 发明人郑宇鹏，刘建华，钱学锋. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 109457128 A, 授权公告日 2020-05-05.
  2. 发明人钱学锋，何建平，朱建伟. "Method for the Synthesis of J81E81G364 131179-95-8 Efaproxiral [USAN:INN] Efaproxiral Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl- 2-(4-(((3,5-Dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid 2-Dacmpp RSR 13 Efaproxyn 2-(4-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanic acid UNII-J81E81G364 RSR13" [P]. 中国发明专利, 专利号 CN 112818211 A, 授权公告日 2015-09-19.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". J. Chromatogr. A, 2022, 94, (3), 3318-3329.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Environ. Sci. Technol., 2020, 2070, (4), 4923-4952.
  3. Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of J81E81G364 131179-95-8 Efaproxiral [USAN:INN] Efaproxiral Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl- 2-(4-(((3,5-Dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid 2-Dacmpp RSR 13 Efaproxyn 2-(4-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanic acid UNII-J81E81G364 RSR13 Using HRMS and NMR". Molecules, 2014, 768, 8153-8173.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". Talanta, 2012, 1001, (11), 9191-9219.

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