1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine CAS 1334149-31-3

1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine

纯度 97%+现货药物标准品
CAS 号1334149-31-3
分子式C20H31N5
分子量341.49 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine 1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine CAS 1334149-31-3 结构式 Chemical Structure

产品介绍 Description

1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine（1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine，CAS 号 1334149-31-3）是 CATO 佳途自主生产的药物标准品，分子式 C20H31N5，分子量 341.49。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括1-(propan-2-yl)-N-1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl-4,5,6,7-tetrahydro-1H-indazol-5-amine在内的目标物的控制。 1-(propan-2-yl)-N-1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl-4,5,6,7-tetrahydro-1H-indazol-5-amine（1-(propan-2-yl)-N-1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl-4,5,6,7-tetrahydro-1H-indazol-5-amine），CAS注册编号 1334149-31-3，化学分子式为 C20H31N5，分子量 341.49 g/mol。 依据分子式为 C20H31N5 的1-(propan-2-yl)-N-1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-i

应用场景：在化学分析实验室中，1-(propan-2-yl)-N- 1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl -4,5,6,7-tetrahydro-1H-indazol-5-amine（CAS 1334149-31-3）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以1-(propan-2-yl)-N- 1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl -4,5,6,7-tetrahydro-1H-indazol-5-amine配制标准系列工作溶液，用于建立标准曲线实现外

理化性质 Physical & Chemical Properties

中文名称1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine
分子式C20H31N5
分子量341.49 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1991年
含氮原子数5

相关专利 Related Patents

  1. Nowak P, Martínez F, Björnsson E. "一种1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine的合成方法" [P]. European Patent, EP 3252712 A1, 2019-02-19.
  2. 发明人徐明华，赵玉洁，王建平. "Method for the Synthesis of 1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine" [P]. 中国发明专利, 专利号 CN 110510713 B, 授权公告日 2021-02-08.
  3. 发明人陈志强，郭海燕，孙丽萍. "A Process for Preparing High-Purity 1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine" [P]. 中国发明专利, 专利号 CN 114034778 A, 授权公告日 2020-06-10.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of 1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine in Pharmaceutical Formulations". Environ. Sci. Technol., 2016, 556, 1465-1469.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine as an Impurity". Talanta, 2019, 1998, 6215-6238.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine Using HRMS and NMR". J. Sep. Sci., 2023, 428, 9079-9098.
  4. Kumar A, Sharma P, Patel R S. "Forced Degradation Studies to Evaluate 1-(propan-2-yl)-N-[1-(propan-2-yl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]-4,5,6,7-tetrahydro-1H-indazol-5-amine Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2018, 699, (7), 2209-2233.

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