5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione CAS 141266-43-5

5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione

纯度 97%+现货药物标准品
CAS 号141266-43-5
分子式C15H10N4O6
分子量342.26 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione 5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione CAS 141266-43-5 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione（5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione）为药物标准品，CAS 登记号 141266-43-5，分子式 C15H10N4O6，分子量 342.26。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno2,3-dpyrimidin-5-yl}-1,3-diazinane-2,4,6-trione在内的目标物的控制。 化学式为 C15H10N4O6 的5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno2,3-dpyrimidin-5-yl}-1,3-diazinane-2,4,6-trione（5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno2,3-dpyrimidin-5-yl}-1,3-diazinane-2,4,6-trione），其CAS登记号是 141266-43-5，分子量为 342.26 g/mol。 依据分子式为 C15H10N4O6 的5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno2,3-dpyrimidin-5-yl}-1,3-diazinane-2,4,6-trione结构特征，其分子内含黄酮骨架，酰胺类，含羟基，含醚键，这意味着该化合物在紫外

应用场景：5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno 2,3-d pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione（5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno 2,3-d pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno 2,3-d pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione配制标准系列工作溶液，用

理化性质 Physical & Chemical Properties

中文名称5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione
分子式C15H10N4O6
分子量342.26 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）13.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1997年
含氮原子数4

相关专利 Related Patents

  1. Martínez F, Lefèvre J P, Sørensen M. "一种5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione的合成方法" [P]. European Patent, EP 3722853 A1, 2016-06-12.
  2. 发明人朱建伟，刘建华，张德明. "Method for the Synthesis of 5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione" [P]. 中国发明专利, 专利号 CN 117891156 B, 授权公告日 2023-09-01.
  3. 发明人沈红梅，杨光，马晓峰. "A Process for Preparing High-Purity 5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione" [P]. 中国发明专利, 专利号 CN 108055963 B, 授权公告日 2023-03-27.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione in Pharmaceutical Formulations". Talanta, 2010, 1887, (8), 6770-6789.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione as an Impurity". Biomed. Chromatogr., 2012, 1010, (1), 3636-3658.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of 5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione Using HRMS and NMR". Chromatographia, 2023, 2164, (5), 148-167.
  4. O'Brien K, Kennedy M L. "Forced Degradation Studies to Evaluate 5-{2,4-dioxo-1H,2H,3H,4H,5H-chromeno[2,3-d]pyrimidin-5-yl}-1,3-diazinane-2,4,6-trione Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2010, 2096, (8), 8685-8698.

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