3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)- CAS 142546-16-5

3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-

纯度 97%+现货药物标准品
CAS 号142546-16-5
分子式C19H20O3
分子量296.36 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)- 3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)- CAS 142546-16-5 结构式 Chemical Structure

产品介绍 Description

3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-（3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-，CAS 号 142546-16-5）是 CATO 佳途自主生产的药物标准品，分子式 C19H20O3，分子量 296.36。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

与同类药物标准品相比，3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-的分子量为296.36 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C19H20O3 的3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-（3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-），其CAS登记号是 142546-16-5，分子量为 296.36 g/mol。 3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-（分子式 C19H20O3）的化学结构中包含甾体骨架，含羟基，含醚键。在反相色谱体系中，其保留行为主要受其较高的疏水性（logP）影响，这为HPLC-UV/DAD或LC-MS方法的

应用场景：针对化学分析用途，3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-（3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-）是具有明确定量溯源的认证级对照品。 推荐以3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测

理化性质 Physical & Chemical Properties

中文名称3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-
分子式C19H20O3
分子量296.36 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1997年

相关专利 Related Patents

  1. 发明人林芳，徐明华，刘建华. "一种3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-的合成方法" [P]. 中国发明专利, 专利号 CN 115402472 B, 授权公告日 2021-06-05.
  2. 发明人赵玉洁，张德明，沈红梅. "Method for the Synthesis of 3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)-" [P]. 中国发明专利, 专利号 CN 116587333 A, 授权公告日 2022-09-15.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)- in Pharmaceutical Formulations". J. Chromatogr. A, 2025, 1959, (7), 3892-3905.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3,4,5(6H)-Phenanthrenetrione, 7,8-dihydro-8,8-dimethyl-2-(1-methylethyl)- as an Impurity". Biomed. Chromatogr., 2010, 2361, (7), 1517-1544.

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