ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate CAS 1461704-82-4

ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate

纯度 97%+现货药物标准品
CAS 号1461704-82-4
分子式C10H12N4O3
分子量236.23 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate CAS 1461704-82-4 结构式 Chemical Structure

产品介绍 Description

ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate（英文名 ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate，CAS 1461704-82-4）属于药物标准品。分子式 C10H12N4O3，分子量 236.23。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，ethyl 1-(3-methyl-1,2,4-oxadiazol-5-yl)methyl-1H-pyrazole-4-carboxylate的分子量为236.23 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C10H12N4O3 的ethyl 1-(3-methyl-1,2,4-oxadiazol-5-yl)methyl-1H-pyrazole-4-carboxylate（ethyl 1-(3-methyl-1,2,4-oxadiazol-5-yl)methyl-1H-pyrazole-4-carboxylate），其CAS登记号是 1461704-82-4，分子量为 236.23 g/mol。 依据分子式为 C10H12N4O3 的ethyl 1-(3-methyl-1,2,4-oxadiazol-5-yl)methyl-1H-pyrazole-4-carboxylate结构特征，其分子内含氨基酸衍生物，酰胺类，含羟基，含醚键，这意味着该化合物在紫外光谱中会呈现特征性的吸收带。分子量 236.23 g/m

应用场景：ethyl 1- (3-methyl-1,2,4-oxadiazol-5-yl)methyl -1H-pyrazole-4-carboxylate（ethyl 1- (3-methyl-1,2,4-oxadiazol-5-yl)methyl -1H-pyrazole-4-carboxylate）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以ethyl 1- (3-methyl-1,2,4-oxadiazol-5-yl)methyl -1H-pyrazole-4-carboxylate配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测

理化性质 Physical & Chemical Properties

中文名称ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate
分子式C10H12N4O3
分子量236.23 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1992年
含氮原子数4

相关专利 Related Patents

  1. Lefèvre J P, Mueller T C, Martínez F. "一种ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate的合成方法" [P]. European Patent, EP 3011061 A1, 2019-01-21.
  2. 发明人冯建国，马晓峰，杨光. "Method for the Synthesis of ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate" [P]. 中国发明专利, 专利号 CN 109723819 B, 授权公告日 2021-05-07.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate in Pharmaceutical Formulations". Phytochemistry, 2020, 1949, (10), 6725-6736.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate as an Impurity". J. Chromatogr. A, 2015, 523, (4), 3682-3696.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate Using HRMS and NMR". J. Pharm. Biomed. Anal., 2025, 1394, (7), 6768-6781.
  4. Martinez C, Lopez D R. "Forced Degradation Studies to Evaluate ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate Profile in Drug Substances According to ICH Guidelines". Talanta, 2024, 1670, (8), 9070-9076.

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