5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride CAS 1461704-87-9

5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride

纯度 97%+现货药物标准品
CAS 号1461704-87-9
分子式C10H15N3O3 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride 5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride CAS 1461704-87-9 结构式 Chemical Structure

产品介绍 Description

5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride（5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride）是药物分析与质量控制领域常用的药物标准品，CAS 号 1461704-87-9。分子式 C10H15N3O3 2*HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

与同类药物标准品相比，5-(4-methylpiperazin-1-yl)methyl-1,2-oxazole-3-carboxylic acid dihydrochloride的分子量为261.71 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 1461704-87-9 对应的化合物5-(4-methylpiperazin-1-yl)methyl-1,2-oxazole-3-carboxylic acid dihydrochloride（英文标识 5-(4-methylpiperazin-1-yl)methyl-1,2-oxazole-3-carboxylic acid dihydrochloride），化学式 C10H15N3O3 2HCl，相对分子质量 261.71。 依据分子式为 C10H15N3O3 2HCl 的5-(4-methylpiperazin-1-yl)methyl-1,2-oxazole-3-carboxylic acid dihydrochloride结构特征，其分子内含含氮杂环结构，酰胺类，含羟基，含

应用场景：5- (4-methylpiperazin-1-yl)methyl -1,2-oxazole-3-carboxylic acid dihydrochloride（5- (4-methylpiperazin-1-yl)methyl -1,2-oxazole-3-carboxylic acid dihydrochloride，CAS 1461704-87-9）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以5- (4-methylpiperazin-1-yl)methyl -1,2-oxazole-3-carboxylic acid dihydrochloride配制标准系列工作溶液，用

理化性质 Physical & Chemical Properties

中文名称5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride
分子式C10H15N3O3 2*HCl
分子量261.71 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1992年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. 发明人郭海燕，林芳，郑宇鹏. "一种5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 110127737 B, 授权公告日 2021-01-25.
  2. Nowak P, Sørensen M, Kowalski A. "Method for the Synthesis of 5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride" [P]. European Patent, EP 3873134 A1, 2015-11-23.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride in Pharmaceutical Formulations". Environ. Sci. Technol., 2016, 1296, (8), 8199-8207.
  2. Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride as an Impurity". Anal. Methods, 2011, 888, 1534-1562.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 5-[(4-methylpiperazin-1-yl)methyl]-1,2-oxazole-3-carboxylic acid dihydrochloride Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2011, 370, 5402-5406.

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