5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid CAS 1803561-85-4

5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid

纯度 97%+现货药物标准品
CAS 号1803561-85-4
分子式C14H22N4O2 CH2O3
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid 5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid CAS 1803561-85-4 结构式 Chemical Structure

产品介绍 Description

5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid（5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid，CAS 号 1803561-85-4）是 CATO 佳途自主生产的药物标准品，分子式 C14H22N4O2 CH2O3。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid在内的目标物的控制。 5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid（5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid），CAS注册编号 1803561-85-4，化学分子式为 C14H22N4O2 CH2O3，分子量 340.38 g/mol。 从化学结构特征来看，5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid的分子骨架中包含含氮杂环结构，酰胺类，含羟基，含醚键。该化

应用场景：针对化学分析用途，5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid（5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid）是具有明确定量溯源的认证级对照品。 推荐以5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid配制标

理化性质 Physical & Chemical Properties

中文名称5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid
分子式C14H22N4O2 CH2O3
分子量340.38 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1995年
含氮原子数4

相关专利 Related Patents

  1. 发明人沈红梅，郑宇鹏，郭海燕. "一种5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid的合成方法" [P]. 中国发明专利, 专利号 CN 110579844 A, 授权公告日 2015-06-13.
  2. 发明人唐晓军，沈红梅，郭海燕. "Method for the Synthesis of 5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid" [P]. 中国发明专利, 专利号 CN 109484769 B, 授权公告日 2024-02-04.
  3. Patel M V, Thompson G K, Yamamoto T. "A Process for Preparing High-Purity 5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid" [P]. US Patent, US 10947784 B2, 2020-12-26.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid in Pharmaceutical Formulations". Food Chem., 2011, 2088, 2511-2540.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid as an Impurity". Rapid Commun. Mass Spectrom., 2017, 2256, (7), 646-654.
  3. Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of 5-(4-hydroxypiperidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid Using HRMS and NMR". Biomed. Chromatogr., 2023, 1898, (11), 9858-9867.

Related hydroxypiperidin Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...