5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride CAS 1803566-08-6

5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride

纯度 97%+现货药物标准品
CAS 号1803566-08-6
分子式C9H15N3O2 HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride 5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride CAS 1803566-08-6 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride（5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride，CAS 1803566-08-6），分子式 C9H15N3O2 HCl。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride的产生途径与其化学式中酰胺类，羧酸类，含羟基，含醚键，含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C9H15N3O2 HCl 的5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride（5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride），其CAS登记号是 1803566-08-6，分子量为 233.70 g/mol。 从化学结构特征来看，5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride的分子骨架中包含酰胺类，羧酸类，含羟基，含醚键，含氯取代。该化合物的不饱和度为3.0，表明结构中存在约3个环或双键等价单元。分子量为233.70

应用场景：5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride（5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride，CAS 1803566-08-6）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1

理化性质 Physical & Chemical Properties

中文名称5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride
分子式C9H15N3O2 HCl
分子量233.70 g/mol
外观形态白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1995年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. 发明人孙丽萍，高志强，陈志强. "一种5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 113877721 B, 授权公告日 2021-01-19.
  2. 发明人赵玉洁，朱建伟，郭海燕. "Method for the Synthesis of 5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride" [P]. 中国发明专利, 专利号 CN 113135020 A, 授权公告日 2022-12-27.
  3. 发明人杨光，冯建国，朱建伟. "A Process for Preparing High-Purity 5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride" [P]. 中国发明专利, 专利号 CN 111671416 A, 授权公告日 2017-12-05.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2015, 1607, 541-564.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride as an Impurity". J. Agric. Food Chem., 2015, 1403, (9), 5551-5557.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of 5-methyl-5-(pyrrolidin-2-ylmethyl)imidazolidine-2,4-dione hydrochloride Using HRMS and NMR". Phytochemistry, 2025, 1243, (6), 7005-7019.

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