5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid CAS 1803590-07-9

5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid

纯度 97%+现货药物标准品
CAS 号1803590-07-9
分子式C13H20N4O2 CH2O3
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid 5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid CAS 1803590-07-9 结构式 Chemical Structure

产品介绍 Description

5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid（5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid，CAS 号 1803590-07-9）是 CATO 佳途自主生产的药物标准品，分子式 C13H20N4O2 CH2O3。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

与同类药物标准品相比，5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid的分子量为326.35 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C13H20N4O2 CH2O3 的5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid（5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid），其CAS登记号是 1803590-07-9，分子量为 326.35 g/mol。 受分子结构中含氮杂环结构，酰胺类，含羟基，含醚键的影响，5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid表现为类白色至淡黄色结晶性粉末。其固体形态的物理化学属性—

应用场景：5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid（5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid，CAS 1803590-07-9）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid配制标准系列工作溶液，用于建立

理化性质 Physical & Chemical Properties

中文名称5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid
分子式C13H20N4O2 CH2O3
分子量326.35 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1995年
含氮原子数4

相关专利 Related Patents

  1. Williams B T, Patel M V, O'Brien P Q. "一种5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid的合成方法" [P]. US Patent, US 11880333 B2, 2021-04-07.
  2. 发明人朱建伟，王建平，冯建国. "Method for the Synthesis of 5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid" [P]. 中国发明专利, 专利号 CN 111467615 A, 授权公告日 2015-08-06.
  3. 发明人王建平，李文辉，高志强. "A Process for Preparing High-Purity 5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid" [P]. 中国发明专利, 专利号 CN 109183965 A, 授权公告日 2021-05-13.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid in Pharmaceutical Formulations". Anal. Chim. Acta, 2020, 744, 5978-6004.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid as an Impurity". Talanta, 2012, 299, (4), 3345-3356.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid Using HRMS and NMR". Anal. Methods, 2023, 375, 9605-9614.
  4. Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate 5-(morpholin-4-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one, carbonic acid Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2011, 2288, 1810-1830.

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