tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate CAS 1803590-45-5

tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate

纯度 97%+现货药物标准品
CAS 号1803590-45-5
分子式-
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate CAS 1803590-45-5 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate（tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate）为药物标准品，CAS 登记号 1803590-45-5，纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在质量保证方面，tert-butyl 3-{(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methylamino}pyrrolidine-1-carboxylate的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 化学式为 （未提供） 的tert-butyl 3-{(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methylamino}pyrrolidine-1-carboxylate（tert-butyl 3-{(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methylamino}pyrrolidine-1-carboxylate），其CAS登记号是 18

应用场景：tert-butyl 3-{ (1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl amino}pyrrolidine-1-carboxylate（tert-butyl 3-{ (1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl amino}pyrrolidine-1-carboxylate）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以tert-butyl 3-{ (1,3-dimethyl-2,4-dioxo-1,2,3,4-

理化性质 Physical & Chemical Properties

中文名称tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate
分子式未提供
分子量未提供
外观形态白色至类白色液体
纯度97%+
储存条件2-8°C冷藏保存
溶解性参考易溶于水
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
CAS登记年份（估）1995年

相关专利 Related Patents

  1. 发明人钱学锋，李文辉，罗永刚. "一种tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate的合成方法" [P]. 中国发明专利, 专利号 CN 111874920 A, 授权公告日 2022-03-19.
  2. Nielsen H, Lefèvre J P, Jørgensen K. "Method for the Synthesis of tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate" [P]. European Patent, EP 3036921 A1, 2015-10-09.
  3. 发明人徐明华，陈志强，张德明. "A Process for Preparing High-Purity tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate" [P]. 中国发明专利, 专利号 CN 108294653 A, 授权公告日 2017-11-10.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate in Pharmaceutical Formulations". Phytochemistry, 2017, 460, (12), 5788-5799.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate as an Impurity". Biomed. Chromatogr., 2013, 746, (9), 3588-3616.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of tert-butyl 3-{[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]amino}pyrrolidine-1-carboxylate Using HRMS and NMR". Environ. Sci. Technol., 2016, 1206, 4336-4355.

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