tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate CAS 1803605-73-3

tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate

纯度 97%+现货药物标准品
CAS 号1803605-73-3
分子式C17H25N3O4
分子量335.40 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate CAS 1803605-73-3 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate（tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate）为药物标准品，CAS 登记号 1803605-73-3，分子式 C17H25N3O4，分子量 335.40。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括tert-butyl 3-{2-(acetamidomethyl)pyridin-4-yloxy}pyrrolidine-1-carboxylate在内的目标物的控制。 CAS编号 1803605-73-3 对应的化合物tert-butyl 3-{2-(acetamidomethyl)pyridin-4-yloxy}pyrrolidine-1-carboxylate（英文标识 tert-butyl 3-{2-(acetamidomethyl)pyridin-4-yloxy}pyrrolidine-1-carboxylate），化学式 C17H25N3O4，相对分子质量 335.40。 tert-butyl 3-{2-(acetamidomethyl)pyridin-4-yloxy}pyrrolidine-1-carboxylate（C17H25N3O4）含有黄酮骨架，酰胺类，含羟基，含醚键。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。分子中包含芳

应用场景：针对化学分析用途，tert-butyl 3-{ 2-(acetamidomethyl)pyridin-4-yl oxy}pyrrolidine-1-carboxylate（tert-butyl 3-{ 2-(acetamidomethyl)pyridin-4-yl oxy}pyrrolidine-1-carboxylate）是具有明确定量溯源的认证级对照品。 推荐以tert-butyl 3-{ 2-(acetamidomethyl)pyridin-4-yl oxy}pyrrolidine-1-carboxylate配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1

理化性质 Physical & Chemical Properties

中文名称tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate
分子式C17H25N3O4
分子量335.40 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1995年
含氮原子数3

相关专利 Related Patents

  1. O'Brien P Q, Fischer A B, Park J H. "一种tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate的合成方法" [P]. US Patent, US 11231777 B2, 2024-01-02.
  2. Fischer A B, Schröder R, Yamamoto T. "Method for the Synthesis of tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate" [P]. US Patent, US 10098715 B2, 2025-06-09.
  3. 发明人钱学锋，郑宇鹏，唐晓军. "A Process for Preparing High-Purity tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate" [P]. 中国发明专利, 专利号 CN 116672439 B, 授权公告日 2016-02-02.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate in Pharmaceutical Formulations". Anal. Methods, 2024, 411, (10), 8694-8706.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate as an Impurity". Chemosphere, 2012, 1936, 2524-2549.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of tert-butyl 3-{[2-(acetamidomethyl)pyridin-4-yl]oxy}pyrrolidine-1-carboxylate Using HRMS and NMR". Biomed. Chromatogr., 2020, 1009, 1984-2013.

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