CAS 183388-64-9

(2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate (2s,3s,5s)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane hemi succinic acid salt (2s,3s,5s)-2-amino-3-hydroxy-5-(tert-butyloxy carbonyl)amino-1,6-diphenylhexane succinate (2s,3s,5s)-5-tert-butyloxycarbonylamino-2-amino -3-hydroxy -1,6-diphenylhexane 1/2 succinate 183388-64-9 BDH succinate salt

纯度 97%+现货药物标准品
CAS 号183388-64-9
分子式2*C23H32N2O3 C4H6O4
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate (2s,3s,5s)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane hemi succinic acid salt (2s,3s,5s)-2-amino-3-hydroxy-5-(tert-butyloxy carbonyl)amino-1,6-diphenylhexane succinate (2s,3s,5s)-5-tert-butyloxycarbonylamino-2-amino -3-hydroxy -1,6-diphenylhexane 1/2 succinate 183388-64-9 BDH succinate salt CAS 183388-64-9 结构式 Chemical Structure

产品介绍 Description

（英文名 (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate (2s,3s,5s)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane hemi succinic acid salt (2s,3s,5s)-2-amino-3-hydroxy-5-(tert-butyloxy carbonyl)amino-1,6-diphenylhexane succinate (2s,3s,5s)-5-tert-butyloxycarbonylamino-2-amino -3-hydroxy -1,6-diphenylhexane 1/2 succinate 183388-64-9 BDH succinate salt，CAS 183388-64-9）属于药物标准品。分子式 2*C23H32N2O3 C4H6O4。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括在内的目标物的控制。 （(2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate (2s,3s,5s)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane hemi succinic acid salt (2s,3s,5s)-2-amino-3-hydroxy-5-(tert-butyloxy carbonyl)amino-1,6-diphenylhexane succinate (2s,3s,5s)-5-tert-butyloxycarbonylamino-2-amino -3-hydroxy -1,6-diphenylhexane 1/2 succinate 183388-64-9 BDH succinate salt），CAS注册编号 183388-64-9，化学分子式为 2C23H32N2O3 C4H6O4，分子量 502.

应用场景：（(2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate (2s,3s,5s)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane hemi succinic acid salt (2s,3s,5s)-2-amino-3-hydroxy-5-(tert-butyloxy carbonyl)amino-1,6-diphenylhexane succinate (2s,3s,5s)-5-tert-buty

理化性质 Physical & Chemical Properties

中文名称
分子式2*C23H32N2O3 C4H6O4
分子量502.61 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2009年
含氮原子数2

相关专利 Related Patents

  1. 发明人孙丽萍，罗永刚，郑宇鹏. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 113563754 A, 授权公告日 2020-01-01.
  2. 发明人张德明，陈志强，郭海燕. "Method for the Synthesis of (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate (2s,3s,5s)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane hemi succinic acid salt (2s,3s,5s)-2-amino-3-hydroxy-5-(tert-butyloxy carbonyl)amino-1,6-diphenylhexane succinate (2s,3s,5s)-5-tert-butyloxycarbonylamino-2-amino -3-hydroxy -1,6-diphenylhexane 1/2 succinate 183388-64-9 BDH succinate salt" [P]. 中国发明专利, 专利号 CN 116180331 B, 授权公告日 2019-04-15.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2010, 220, 2481-2491.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Methods, 2010, 204, 9607-9623.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of (2S,3S,5S)-5-tert-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane succinate (2s,3s,5s)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane hemi succinic acid salt (2s,3s,5s)-2-amino-3-hydroxy-5-(tert-butyloxy carbonyl)amino-1,6-diphenylhexane succinate (2s,3s,5s)-5-tert-butyloxycarbonylamino-2-amino -3-hydroxy -1,6-diphenylhexane 1/2 succinate 183388-64-9 BDH succinate salt Using HRMS and NMR". Food Chem., 2016, 82, (5), 8242-8247.
  4. Zhang Y, Li Q, Chen T. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2012, 997, 3265-3274.

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