5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride CAS 1955492-47-3

5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride

纯度 97%+现货药物标准品
CAS 号1955492-47-3
分子式C14H26N2O3 HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride 5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride CAS 1955492-47-3 结构式 Chemical Structure

产品介绍 Description

5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride(5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride)是药物分析与质量控制领域常用的药物标准品,CAS 号 1955492-47-3。分子式 C14H26N2O3 HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录,可一站式满足配套采购需求。

与同类药物标准品相比,5-methyl-3-(piperidin-2-ylformamido)methylhexanoic acid hydrochloride的分子量为306.83 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 5-methyl-3-(piperidin-2-ylformamido)methylhexanoic acid hydrochloride(5-methyl-3-(piperidin-2-ylformamido)methylhexanoic acid hydrochloride),CAS注册编号 1955492-47-3,化学分子式为 C14H26N2O3 HCl,分子量 306.83 g/mol。 5-methyl-3-(piperidin-2-ylformamido)methylhexanoic acid hydrochloride(C14H26N2O3 HCl)含有酰胺类,羧酸类,含羟基,含醚键,含氯取代。具有较强的吸湿性,卤素取代增加了化合物的密度和沸点,羧基赋予其一定的酸性特征,这些物理化学性质直接决定了其

应用场景:针对化学分析用途,5-methyl-3- (piperidin-2-ylformamido)methyl hexanoic acid hydrochloride(5-methyl-3- (piperidin-2-ylformamido)methyl hexanoic acid hydrochloride)是具有明确定量溯源的认证级对照品。 推荐以5-methyl-3- (piperidin-2-ylformamido)methyl hexanoic acid hydrochloride配制标准系列工作溶液,用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈(1:1)为溶剂配制储备溶液,根据

理化性质 Physical & Chemical Properties

中文名称5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride
分子式C14H26N2O3 HCl
分子量306.83 g/mol
外观形态白色至类白色结晶性粉末。(具有轻微卤代物特征气味)
纯度97%+
储存条件2-8°C冷藏保存,避光,密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感,应避免强光直射;具有吸湿性,开封后应立即密封;含酯键,遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)2.0
CAS登记年份(估)1996年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. 发明人孙丽萍,韩伟,周伟. "一种5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride的合成方法" [P]. 中国发明专利, 专利号 CN 108202278 A, 授权公告日 2023-03-09.
  2. 发明人刘建华,何建平,林芳. "Method for the Synthesis of 5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride" [P]. 中国发明专利, 专利号 CN 111760102 A, 授权公告日 2015-06-05.
  3. 发明人孙丽萍,郑宇鹏,罗永刚. "A Process for Preparing High-Purity 5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride" [P]. 中国发明专利, 专利号 CN 111350128 B, 授权公告日 2020-01-24.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of 5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride in Pharmaceutical Formulations". Phytochemistry, 2017, 320, 7997-8016.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride as an Impurity". Sci. Total Environ., 2016, 94, (7), 955-974.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride Using HRMS and NMR". Food Chem., 2017, 956, 1937-1966.
  4. Jensen P, Larsen A M, Olsen K. "Forced Degradation Studies to Evaluate 5-methyl-3-[(piperidin-2-ylformamido)methyl]hexanoic acid hydrochloride Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2025, 1873, 6991-7002.

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