rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride CAS 1969288-67-2

rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride

纯度 97%+现货药物标准品
CAS 号1969288-67-2
分子式C11H17N3O 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride CAS 1969288-67-2 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride（rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride）为药物标准品，CAS 登记号 1969288-67-2，分子式 C11H17N3O 2*HCl。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，rac-(2R,3R)-2-1-(cyclopropylmethyl)-1H-pyrazol-5-yloxolan-3-amine dihydrochloride的分子量为243.73 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C11H17N3O 2HCl 的rac-(2R,3R)-2-1-(cyclopropylmethyl)-1H-pyrazol-5-yloxolan-3-amine dihydrochloride（rac-(2R,3R)-2-1-(cyclopropylmethyl)-1H-pyrazol-5-yloxolan-3-amine dihydrochloride），其CAS登记号是 1969288-67-2，分子量为 243.73 g/mol。 rac-(2R,3R)-2-1-(cyclopropylmethyl)-1H-pyrazol-5-yloxolan-3-amine dihydrochloride（分子式 C11H17N3O 2HCl）的化学结构中包含含氮杂环结构，酰胺类，含羟

应用场景：针对化学分析用途，rac-(2R,3R)-2- 1-(cyclopropylmethyl)-1H-pyrazol-5-yl oxolan-3-amine dihydrochloride（rac-(2R,3R)-2- 1-(cyclopropylmethyl)-1H-pyrazol-5-yl oxolan-3-amine dihydrochloride）是具有明确定量溯源的认证级对照品。 推荐以rac-(2R,3R)-2- 1-(cyclopropylmethyl)-1H-pyrazol-5-yl oxolan-3-amine dihydrochloride配制标准系列工作溶液，用于建立标准曲

理化性质 Physical & Chemical Properties

中文名称rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride
分子式C11H17N3O 2*HCl
分子量243.73 g/mol
外观形态类白色至淡黄色低熔点固体。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1996年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. Klinger H, Anderson J P, Schröder R. "一种rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride的合成方法" [P]. US Patent, US 9750579 B2, 2021-07-06.
  2. 发明人孙丽萍，杨光，沈红梅. "Method for the Synthesis of rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride" [P]. 中国发明专利, 专利号 CN 116082181 B, 授权公告日 2025-08-07.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2011, 2066, (6), 9301-9325.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride as an Impurity". Anal. Chem., 2024, 631, (8), 1842-1852.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride Using HRMS and NMR". Anal. Methods, 2024, 1216, (4), 6289-6307.
  4. Yamamoto K, Tanaka H, Suzuki T. "Forced Degradation Studies to Evaluate rac-(2R,3R)-2-[1-(cyclopropylmethyl)-1H-pyrazol-5-yl]oxolan-3-amine dihydrochloride Profile in Drug Substances According to ICH Guidelines". Food Chem., 2018, 1768, 1549-1564.

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