Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700 CAS 203714-71-0

Hoveyda-Grubbs Catalyst 1st Generation 203714-71-0 DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II);DICHLORO[[2-(1-METHYLETHOXY-O)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;HOVEYDA-GRUBBS CATALYST 1ST GENERATION;RUTHENIUM, DICHLORO[[2-(1-METHYLETHOXY)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE) SC10094

纯度 97%+现货药物标准品
CAS 号203714-71-0
分子式C10H18Cl2ORu C18H33P
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700 Hoveyda-Grubbs Catalyst 1st Generation 203714-71-0 DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II);DICHLORO[[2-(1-METHYLETHOXY-O)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;HOVEYDA-GRUBBS CATALYST 1ST GENERATION;RUTHENIUM, DICHLORO[[2-(1-METHYLETHOXY)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE) SC10094 CAS 203714-71-0 结构式 Chemical Structure

产品介绍 Description

Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700（英文名 Hoveyda-Grubbs Catalyst 1st Generation 203714-71-0 DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II);DICHLORO[[2-(1-METHYLETHOXY-O)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;HOVEYDA-GRUBBS CATALYST 1ST GENERATION;RUTHENIUM, DICHLORO[[2-(1-METHYLETHOXY)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE) SC10094，CAS 203714-71-0）属于药物标准品。分子式 C10H18Cl2ORu C18H33P。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700的分子量为606.66 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700（Hoveyda-Grubbs Catalyst 1st Generation 203714-71-0 DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II);DICHLORO2-(1-METHYLETHOXY-O)PHENYLMETHYLENE(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;HOVEYDA-GRUBBS CATALYST 1ST GENERATION;RUTHENIUM, DICHLORO2-(1-METHYLETHOXY)PHENYLMETHYLENE(TRICYCLOHEXYLPHOSPHINE) SC10094），CAS注册编号 203714-71-0，化学分子

应用场景：在化学分析实验室中，Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700（CAS 203714-71-0）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放；

理化性质 Physical & Chemical Properties

中文名称Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700
分子式C10H18Cl2ORu C18H33P
分子量606.66 g/mol
外观形态白色至类白色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.5
CAS登记年份（估）2015年
卤素含量Cl取代

相关专利 Related Patents

  1. 发明人韩伟，杨光，唐晓军. "一种Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700的合成方法" [P]. 中国发明专利, 专利号 CN 116856072 B, 授权公告日 2016-10-06.
  2. Jørgensen K, Mueller T C, Nielsen H. "Method for the Synthesis of Hoveyda-Grubbs Catalyst 1st Generation 203714-71-0 DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II);DICHLORO[[2-(1-METHYLETHOXY-O)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;HOVEYDA-GRUBBS CATALYST 1ST GENERATION;RUTHENIUM, DICHLORO[[2-(1-METHYLETHOXY)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE) SC10094" [P]. European Patent, EP 3299433 A1, 2021-09-17.
  3. 发明人孙丽萍，徐明华，王建平. "A Process for Preparing High-Purity Hoveyda-Grubbs Catalyst 1st Generation 203714-71-0 DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II);DICHLORO[[2-(1-METHYLETHOXY-O)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE)RUTHENIUM;HOVEYDA-GRUBBS CATALYST 1ST GENERATION;RUTHENIUM, DICHLORO[[2-(1-METHYLETHOXY)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE) SC10094" [P]. 中国发明专利, 专利号 CN 113961309 B, 授权公告日 2017-03-02.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700 in Pharmaceutical Formulations". Chromatographia, 2014, 1131, 2184-2199.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of Hoveyda-Grubbs Catalyst<SUP>®</SUP> M700 as an Impurity". Environ. Sci. Technol., 2014, 1394, (4), 1781-1806.

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