CAS 210759-10-7

(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

纯度 97%+现货药物标准品
CAS 号210759-10-7
分子式C66H120N12O13S
分子量1321.80 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone CAS 210759-10-7 结构式 Chemical Structure

产品介绍 Description

CAS 210759-10-7 对应的（(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone）为 CATO 佳途药物标准品产品线成员。分子式 C66H120N12O13S，分子量 1321.80。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

受分子结构中含氮杂环结构，酰胺类，含砜基，含羟基，含醚键的影响，表现为淡黄色至黄色无定形粉末。（含硫化合物特征性气味）。其固体形态的物理化学属性——包括1321.80 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。由于结构中存在共轭发色团，该化合物在200-400 nm区间具有显著的紫外吸收，便于HPLC-UV检测。 化学式为 C66H120N12O13S 的（(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14

应用场景：针对化学分析用途，（(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriaconta

理化性质 Physical & Chemical Properties

中文名称
分子式C66H120N12O13S
分子量1321.80 g/mol
外观形态淡黄色至黄色无定形粉末。（含硫化合物特征性气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）13.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2017年
含氮原子数12
含硫原子数1

相关专利 Related Patents

  1. 发明人孙丽萍，朱建伟，刘建华. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 116374836 B, 授权公告日 2023-09-21.
  2. Brown S R, Chen K W, Klinger H. "Method for the Synthesis of (3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone" [P]. US Patent, US 9121554 B2, 2019-04-20.
  3. 发明人孙丽萍，韩伟，唐晓军. "A Process for Preparing High-Purity (3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone" [P]. 中国发明专利, 专利号 CN 114009650 A, 授权公告日 2015-01-02.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Food Chem., 2010, 602, 9030-9042.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Phytochemistry, 2015, 908, 9061-9080.

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