tert-Butyl (2-piperidin-3-ylethyl)carbamate CAS 215305-98-9

3-(N-Boc-aminoethyl)piperidine 3-(2-boc-aminoethyl) piperidine (2-piperidin-3-yl-ethyl)-carbamic acid tert-butyl ester 3-(n-boc-aminoethyl)-piperidine 3-(2-boc-aminoethyl)piperidine carbamic acid, n-[2-(3-piperidinyl)ethyl]-, 1,1-dimethylethyl ester 3-(n-boc-2-aminoethyl)piperidine tert-butyl n-[2-(piperidin-3-yl)ethyl]carbamate 215305-98-9

纯度 97%+现货药物标准品
CAS 号215305-98-9
分子式C12H24N2O2
分子量228.33 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

tert-Butyl (2-piperidin-3-ylethyl)carbamate 3-(N-Boc-aminoethyl)piperidine 3-(2-boc-aminoethyl) piperidine (2-piperidin-3-yl-ethyl)-carbamic acid tert-butyl ester 3-(n-boc-aminoethyl)-piperidine 3-(2-boc-aminoethyl)piperidine carbamic acid, n-[2-(3-piperidinyl)ethyl]-, 1,1-dimethylethyl ester 3-(n-boc-2-aminoethyl)piperidine tert-butyl n-[2-(piperidin-3-yl)ethyl]carbamate 215305-98-9 CAS 215305-98-9 结构式 Chemical Structure

产品介绍 Description

CAS 215305-98-9 对应的tert-Butyl (2-piperidin-3-ylethyl)carbamate（3-(N-Boc-aminoethyl)piperidine 3-(2-boc-aminoethyl) piperidine (2-piperidin-3-yl-ethyl)-carbamic acid tert-butyl ester 3-(n-boc-aminoethyl)-piperidine 3-(2-boc-aminoethyl)piperidine carbamic acid, n-[2-(3-piperidinyl)ethyl]-, 1,1-dimethylethyl ester 3-(n-boc-2-aminoethyl)piperidine tert-butyl n-[2-(piperidin-3-yl)ethyl]carbamate 215305-98-9）为 CATO 佳途药物标准品产品线成员。分子式 C12H24N2O2，分子量 228.33。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 tert-Butyl (2-piperidin-3-ylethyl)carbamate（3-(N-Boc-aminoethyl)piperidine 3-(2-boc-aminoethyl) piperidine (2-piperidin-3-yl-ethyl)-carbamic acid tert-butyl ester 3-(n-boc-aminoethyl)-piperidine 3-(2-boc-aminoethyl)piperidine carbamic acid, n-2-(3-piperidinyl)ethyl-, 1,1-dimethylethyl ester 3-(n-boc-2-aminoethyl)piperidine tert-butyl n-2-(piperidin-3-yl)ethylcarbamate 215305-98-9），CAS注册编号 215305-98-9，化学分子式为 C12H24N2O2，分子量 228.3

应用场景：tert-Butyl (2-piperidin-3-ylethyl)carbamate（3-(N-Boc-aminoethyl)piperidine 3-(2-boc-aminoethyl) piperidine (2-piperidin-3-yl-ethyl)-carbamic acid tert-butyl ester 3-(n-boc-aminoethyl)-piperidine 3-(2-boc-aminoethyl)piperidine carbamic acid, n- 2-(3-piperidinyl)ethyl -, 1,1-dimethylethyl ester 3-(n-b

理化性质 Physical & Chemical Properties

中文名称tert-Butyl (2-piperidin-3-ylethyl)carbamate
分子式C12H24N2O2
分子量228.33 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）2018年
含氮原子数2

相关专利 Related Patents

  1. Patel M V, Thompson G K, Davis P L. "一种tert-Butyl (2-piperidin-3-ylethyl)carbamate的合成方法" [P]. US Patent, US 9808227 B2, 2019-11-21.
  2. 发明人罗永刚，徐明华，高志强. "Method for the Synthesis of 3-(N-Boc-aminoethyl)piperidine 3-(2-boc-aminoethyl) piperidine (2-piperidin-3-yl-ethyl)-carbamic acid tert-butyl ester 3-(n-boc-aminoethyl)-piperidine 3-(2-boc-aminoethyl)piperidine carbamic acid, n-[2-(3-piperidinyl)ethyl]-, 1,1-dimethylethyl ester 3-(n-boc-2-aminoethyl)piperidine tert-butyl n-[2-(piperidin-3-yl)ethyl]carbamate 215305-98-9" [P]. 中国发明专利, 专利号 CN 108579853 B, 授权公告日 2019-04-11.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of tert-Butyl (2-piperidin-3-ylethyl)carbamate in Pharmaceutical Formulations". Chromatographia, 2021, 1434, 5880-5909.
  2. Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of tert-Butyl (2-piperidin-3-ylethyl)carbamate as an Impurity". Rapid Commun. Mass Spectrom., 2013, 1729, 8824-8853.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of 3-(N-Boc-aminoethyl)piperidine 3-(2-boc-aminoethyl) piperidine (2-piperidin-3-yl-ethyl)-carbamic acid tert-butyl ester 3-(n-boc-aminoethyl)-piperidine 3-(2-boc-aminoethyl)piperidine carbamic acid, n-[2-(3-piperidinyl)ethyl]-, 1,1-dimethylethyl ester 3-(n-boc-2-aminoethyl)piperidine tert-butyl n-[2-(piperidin-3-yl)ethyl]carbamate 215305-98-9 Using HRMS and NMR". J. Chromatogr. A, 2018, 1201, (6), 7556-7566.

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