CAS 216863-66-0

862SGU1BRL 216863-66-0 L 756423 D-erythro-Pentonamide, 5-((2S)-4-(2-benzofuranylmethyl)-2-(((1,1-dimethylethyl)amino)carbonyl)-1-piperazinyl)-2,3,5-trideoxy-N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(phenylmethyl)- MK 944a L-756423 N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydroxy-5-(1-(4-(2-benzo(b)furanylmethyl)-2(S)-N'-(tert-butylcarboxamido)piperazinyl))pentanamide UNII-862SGU1BRL

纯度 97%+现货药物标准品
CAS 号216863-66-0
分子式C39H48N4O5
分子量652.82 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

862SGU1BRL 216863-66-0 L 756423 D-erythro-Pentonamide, 5-((2S)-4-(2-benzofuranylmethyl)-2-(((1,1-dimethylethyl)amino)carbonyl)-1-piperazinyl)-2,3,5-trideoxy-N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(phenylmethyl)- MK 944a L-756423 N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydroxy-5-(1-(4-(2-benzo(b)furanylmethyl)-2(S)-N'-(tert-butylcarboxamido)piperazinyl))pentanamide UNII-862SGU1BRL CAS 216863-66-0 结构式 Chemical Structure

产品介绍 Description

（862SGU1BRL 216863-66-0 L 756423 D-erythro-Pentonamide, 5-((2S)-4-(2-benzofuranylmethyl)-2-(((1,1-dimethylethyl)amino)carbonyl)-1-piperazinyl)-2,3,5-trideoxy-N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(phenylmethyl)- MK 944a L-756423 N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydroxy-5-(1-(4-(2-benzo(b)furanylmethyl)-2(S)-N'-(tert-butylcarboxamido)piperazinyl))pentanamide UNII-862SGU1BRL，CAS 号 216863-66-0）是 CATO 佳途自主生产的药物标准品，分子式 C39H48N4O5，分子量 652.82。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

与同类药物标准品相比，的分子量为652.82 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 （862SGU1BRL 216863-66-0 L 756423 D-erythro-Pentonamide, 5-((2S)-4-(2-benzofuranylmethyl)-2-(((1,1-dimethylethyl)amino)carbonyl)-1-piperazinyl)-2,3,5-trideoxy-N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(phenylmethyl)- MK 944a L-756423 N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydroxy-5-(1-(4-(2-benzo(b)furanylmethyl)-2(S)-N'-(tert-butylcarboxamido)piperazinyl))pentanamide UNII-862SGU1BRL），CAS注册编号 216863-66-0，化学分子式为 C39H4

应用场景：（862SGU1BRL 216863-66-0 L 756423 D-erythro-Pentonamide, 5-((2S)-4-(2-benzofuranylmethyl)-2-(((1,1-dimethylethyl)amino)carbonyl)-1-piperazinyl)-2,3,5-trideoxy-N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(phenylmethyl)- MK 944a L-756423 N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydrox

理化性质 Physical & Chemical Properties

中文名称
分子式C39H48N4O5
分子量652.82 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）18.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2018年
含氮原子数4

相关专利 Related Patents

  1. 发明人赵玉洁，罗永刚，何建平. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 110996863 A, 授权公告日 2015-07-12.
  2. 发明人冯建国，何建平，钱学锋. "Method for the Synthesis of 862SGU1BRL 216863-66-0 L 756423 D-erythro-Pentonamide, 5-((2S)-4-(2-benzofuranylmethyl)-2-(((1,1-dimethylethyl)amino)carbonyl)-1-piperazinyl)-2,3,5-trideoxy-N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(phenylmethyl)- MK 944a L-756423 N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydroxy-5-(1-(4-(2-benzo(b)furanylmethyl)-2(S)-N'-(tert-butylcarboxamido)piperazinyl))pentanamide UNII-862SGU1BRL" [P]. 中国发明专利, 专利号 CN 116405733 A, 授权公告日 2019-11-23.
  3. 发明人黄志刚，罗永刚，郭海燕. "A Process for Preparing High-Purity 862SGU1BRL 216863-66-0 L 756423 D-erythro-Pentonamide, 5-((2S)-4-(2-benzofuranylmethyl)-2-(((1,1-dimethylethyl)amino)carbonyl)-1-piperazinyl)-2,3,5-trideoxy-N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(phenylmethyl)- MK 944a L-756423 N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydroxy-5-(1-(4-(2-benzo(b)furanylmethyl)-2(S)-N'-(tert-butylcarboxamido)piperazinyl))pentanamide UNII-862SGU1BRL" [P]. 中国发明专利, 专利号 CN 109829285 A, 授权公告日 2019-08-12.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". J. Sep. Sci., 2019, 1684, (10), 4825-4852.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". J. Nat. Prod., 2013, 1077, 392-398.

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