(<I>S</I>)-RuCl[(<I>p</I>-异丙基)(T-BINAP)]Cl CAS 228120-95-4

Chloro[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride, [RuCl(p-cymene)((S)-tolbinap)]Cl 228120-95-4 (R)-RUCL[(P-CYMENE)(T-BINAP)]CL;(S)-RUCL[(P-CYMENE)(T-BINAP)]CL;CHLORO[(R)-(+)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL](P-CYMENE)RUTHENIUM(II) CHLORIDE;CHLORO[(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL](P-CYMENE)RUTHENIUM(II) CHLORIDE;[RUCL(P-CYMENE)((R)-TOLBINAP)]CL;[RUCL(P-CYMENE)((S)-TOLBINAP)]CL;Chloro[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride, [RuCl(p-cymene)((S)-tolbinap)]Cl SC10123

纯度 97%+现货药物标准品
CAS 号228120-95-4
分子式C48H84P2 ClRu C10H14 Cl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(<I>S</I>)-RuCl[(<I>p</I>-异丙基)(T-BINAP)]Cl Chloro[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride, [RuCl(p-cymene)((S)-tolbinap)]Cl 228120-95-4 (R)-RUCL[(P-CYMENE)(T-BINAP)]CL;(S)-RUCL[(P-CYMENE)(T-BINAP)]CL;CHLORO[(R)-(+)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL](P-CYMENE)RUTHENIUM(II) CHLORIDE;CHLORO[(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL](P-CYMENE)RUTHENIUM(II) CHLORIDE;[RUCL(P-CYMENE)((R)-TOLBINAP)]CL;[RUCL(P-CYMENE)((S)-TOLBINAP)]CL;Chloro[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride, [RuCl(p-cymene)((S)-tolbinap)]Cl SC10123 CAS 228120-95-4 结构式 Chemical Structure

产品介绍 Description

(<I>S</I>)-RuCl[(<I>p</I>-异丙基)(T-BINAP)]Cl（Chloro[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride, [RuCl(p-cymene)((S)-tolbinap)]Cl 228120-95-4 (R)-RUCL[(P-CYMENE)(T-BINAP)]CL;(S)-RUCL[(P-CYMENE)(T-BINAP)]CL;CHLORO[(R)-(+)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL](P-CYMENE)RUTHENIUM(II) CHLORIDE;CHLORO[(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL](P-CYMENE)RUTHENIUM(II) CHLORIDE;[RUCL(P-CYMENE)((R)-TOLBINAP)]CL;[RUCL(P-CYMENE)((S)-TOLBINAP)]CL;Chloro[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride, [RuCl(p-cymene)((S)-tolbinap)]Cl SC10123，CAS 号 228120-95-4）是 CATO 佳途自主生产的药物标准品，分子式 C48H84P2 ClRu C10H14 Cl。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括(<I>S</I>)-RuCl(<I>p</I>-异丙基)(T-BINAP)Cl在内的目标物的控制。 CAS编号 228120-95-4 对应的化合物(<I>S</I>)-RuCl(<I>p</I>-异丙基)(T-BINAP)Cl（英文标识 Chloro(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl(p-cymene)ruthenium(II) chloride, RuCl(p-cymene)((S)-tolbinap)Cl 228120-95-4 (R)-RUCL(P-CYMENE)(T-BINAP)CL;(S)-RUCL(P-CYMENE)(T-BINAP)CL;CHLORO(R)-(+)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL(P-CYMENE)RUTHENIUM(II) CHLORIDE;CHLORO(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1

应用场景：(<I>S</I>)-RuCl (<I>p</I>-异丙基)(T-BINAP) Cl（Chloro (S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl (p-cymene)ruthenium(II) chloride, RuCl(p-cymene)((S)-tolbinap) Cl 228120-95-4 (R)-RUCL (P-CYMENE)(T-BINAP) CL;(S)-RUCL (P-CYMENE)(T-BINAP) CL;CHLORO (R)-(+)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BIN

理化性质 Physical & Chemical Properties

中文名称(<I>S</I>)-RuCl[(<I>p</I>-异丙基)(T-BINAP)]Cl
分子式C48H84P2 ClRu C10H14 Cl
分子量1029.34 g/mol
外观形态淡黄色至黄色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2022年
卤素含量Cl取代

相关专利 Related Patents

  1. 发明人陈志强，唐晓军，胡光. "一种(<I>S</I>)-RuCl[(<I>p</I>-异丙基)(T-BINAP)]Cl的合成方法" [P]. 中国发明专利, 专利号 CN 116332560 B, 授权公告日 2024-04-17.
  2. 发明人郑宇鹏，韩伟，罗永刚. "Method for the Synthesis of Chloro[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride, [RuCl(p-cymene)((S)-tolbinap)]Cl 228120-95-4 (R)-RUCL[(P-CYMENE)(T-BINAP)]CL;(S)-RUCL[(P-CYMENE)(T-BINAP)]CL;CHLORO[(R)-(+)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL](P-CYMENE)RUTHENIUM(II) CHLORIDE;CHLORO[(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL](P-CYMENE)RUTHENIUM(II) CHLORIDE;[RUCL(P-CYMENE)((R)-TOLBINAP)]CL;[RUCL(P-CYMENE)((S)-TOLBINAP)]CL;Chloro[(S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride, [RuCl(p-cymene)((S)-tolbinap)]Cl SC10123" [P]. 中国发明专利, 专利号 CN 108442030 A, 授权公告日 2023-03-15.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of (<I>S</I>)-RuCl[(<I>p</I>-异丙基)(T-BINAP)]Cl in Pharmaceutical Formulations". Biomed. Chromatogr., 2013, 1634, 646-652.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of (<I>S</I>)-RuCl[(<I>p</I>-异丙基)(T-BINAP)]Cl as an Impurity". Rapid Commun. Mass Spectrom., 2021, 247, (11), 3652-3662.

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