PhDave-Phos CAS 240417-00-9
2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl 240417-00-9 2'-(DIPHENYLPHOSPHINO)-N,N'-DIMETHYL-(1,1'-BIPHENYL)-2-AMINE;2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLBIPHENYL-2-AMINE;2-DIMETHYLAMINO-2'-(DIPHENYLPHOSPHINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-DIMETHYLAMINOBIPHENYL;PHDAVEPHOS;[1,1'-BIPHENYL]-2-AMINE, 2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYL- GC10114
| CAS 号 | 240417-00-9 |
| 分子式 | C26H48NP |
| 分子量 | 405.64 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CATO 佳途供应的PhDave-Phos（2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl 240417-00-9 2'-(DIPHENYLPHOSPHINO)-N,N'-DIMETHYL-(1,1'-BIPHENYL)-2-AMINE;2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLBIPHENYL-2-AMINE;2-DIMETHYLAMINO-2'-(DIPHENYLPHOSPHINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-DIMETHYLAMINOBIPHENYL;PHDAVEPHOS;[1,1'-BIPHENYL]-2-AMINE, 2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYL- GC10114）为药物标准品，CAS 登记号 240417-00-9，分子式 C26H48NP，分子量 405.64。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。
与同类药物标准品相比，PhDave-Phos的分子量为405.64 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C26H48NP 的PhDave-Phos（2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl 240417-00-9 2'-(DIPHENYLPHOSPHINO)-N,N'-DIMETHYL-(1,1'-BIPHENYL)-2-AMINE;2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLBIPHENYL-2-AMINE;2-DIMETHYLAMINO-2'-(DIPHENYLPHOSPHINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-DIMETHYLAMINOBIPHENYL;PHDAVEPHOS;1,1'-BIPHENYL-2-AMINE, 2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYL- GC10114），其C
应用场景：在化学分析实验室中，PhDave-Phos（CAS 240417-00-9）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以PhDave-Phos配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存，避光条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | PhDave-Phos |
| 分子式 | C26H48NP |
| 分子量 | 405.64 g/mol |
| 外观形态 | 白色至淡黄色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 室温保存，避光 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯 |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 3.5 |
| UV特征 | 有紫外吸收 |
| CAS登记年份（估） | 2025年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- Stevens L M, Chen K W, Lee S K. "一种PhDave-Phos的合成方法" [P]. US Patent, US 10815683 B2, 2022-10-17.
- 发明人刘建华，周伟，陈志强. "Method for the Synthesis of 2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl 240417-00-9 2'-(DIPHENYLPHOSPHINO)-N,N'-DIMETHYL-(1,1'-BIPHENYL)-2-AMINE;2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLBIPHENYL-2-AMINE;2-DIMETHYLAMINO-2'-(DIPHENYLPHOSPHINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-DIMETHYLAMINOBIPHENYL;PHDAVEPHOS;[1,1'-BIPHENYL]-2-AMINE, 2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYL- GC10114" [P]. 中国发明专利, 专利号 CN 117742789 B, 授权公告日 2025-02-22.
- Jørgensen K, Sørensen M, Schröder R. "A Process for Preparing High-Purity 2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl 240417-00-9 2'-(DIPHENYLPHOSPHINO)-N,N'-DIMETHYL-(1,1'-BIPHENYL)-2-AMINE;2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLBIPHENYL-2-AMINE;2-DIMETHYLAMINO-2'-(DIPHENYLPHOSPHINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL;2-DIPHENYLPHOSPHINO-2'-DIMETHYLAMINOBIPHENYL;PHDAVEPHOS;[1,1'-BIPHENYL]-2-AMINE, 2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYL- GC10114" [P]. European Patent, EP 3580910 A1, 2020-09-08.
参考文献 Literature
- Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of PhDave-Phos in Pharmaceutical Formulations". Food Chem., 2020, 794, 7563-7587.
- O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of PhDave-Phos as an Impurity". J. Pharm. Biomed. Anal., 2019, 113, (2), 2915-2918.
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